Frequent somatic mutations of the β-catenin gene in intestinal-type gastric cancer

The increased level of cytoplasmic beta-catenin through the mutations to either beta-catenin or adenomatous polyposis coli (APC) has been proposed as an important oncogenic step in various tumors. Gastric cancer showed frequent genetic alterations of the APC gene, and the risk for gastric cancer in...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1999-09, Vol.59 (17), p.4257-4260
Hauptverfasser:	Park, W S, Oh, R R, Park, J Y, Lee, S H, Shin, M S, Kim, Y S, Kim, S Y, Lee, H K, Kim, P J, Oh, S T, Yoo, N J, Lee, J Y
Format:	Artikel
Sprache:	eng
Schlagworte:	adenomatous polyposis coli APC gene b-catenin Base Sequence beta Catenin Biological and medical sciences Cytoskeletal Proteins - genetics gastric carcinoma Gastroenterology. Liver. Pancreas. Abdomen Genes, APC Humans Medical sciences Molecular Sequence Data Mutation, Missense Stomach Neoplasms - genetics Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Trans-Activators Tumors
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