The Transcription Factor Sox9 Is Involved in BMP‐2 Signaling

We investigated the regulation of Sox9, a transcription factor known to play a role in chondrogenesis, by bone morphogenetic protein‐2 (BMP‐2) and hedgehog proteins in order to better understand their signaling function in endochondral bone formation. The mesenchymal progenitor cell line C3H10T1/2 w...

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Veröffentlicht in:	Journal of bone and mineral research 1999-10, Vol.14 (10), p.1734-1741
Hauptverfasser:	Zehentner, Barbara K., Dony, Carola, Burtscher, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Morphogenetic Protein 2 Bone Morphogenetic Proteins - physiology Cells, Cultured Chondrogenesis - physiology Fundamental and applied biological sciences. Psychology High Mobility Group Proteins - physiology Humans Mice Reverse Transcriptase Polymerase Chain Reaction Signal Transduction - physiology Skeleton and joints SOX9 Transcription Factor Transcription Factors - physiology Transforming Growth Factor beta Tumor Cells, Cultured Vertebrates: osteoarticular system, musculoskeletal system
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