Intracranial vascular stenosis and occlusion : comparison of 3D time-of-flight and 3D phase-contrast MR angiography
We compared the value of 3D time-of-flight (TOF) and phase-contrast (PC) MR angiography (MRA) for detection and grading of intracranial vascular steno-occlusive disease. Unenhanced 3D-TOF MRA and 3D-PC MRA (30-60 cm/s velocity encoding) were performed at the level of the circle of Willis in 18 patie...
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| Veröffentlicht in: | Neuroradiology 1998-09, Vol.40 (9), p.567-573 |
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| container_title | Neuroradiology |
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| creator | OELERICH, M LENTSCHIG, M. G ZUNKER, P REIMER, P RUMMENY, E. J SCHUIERER, G |
| description | We compared the value of 3D time-of-flight (TOF) and phase-contrast (PC) MR angiography (MRA) for detection and grading of intracranial vascular steno-occlusive disease. Unenhanced 3D-TOF MRA and 3D-PC MRA (30-60 cm/s velocity encoding) were performed at the level of the circle of Willis in 18 patients, mean age 56 +/- 10 years. Postprocessed images using a maximum-intensity projection reconstruction with multiple targetted projections were analysed. A total of 126 vessels was assessed by PC MRA and 143 by TOF MRA, with digital subtraction angiography (DSA) in 15 patients and/or transcranial Doppler sonography (TCD) in 18 as a standard. Two blinded readers reviewed the MRA, DSA and TCD examinations retrospectively. On DSA and/or TCD the two observers found 32 and 28 steno-occlusive lesions. 3D-TOF MRA was more sensitive than 3D-PC MRA (87% and 86% vs. 65% and 60%) and had a higher negative predictive value (96% vs. 89%). Correct grading of stenoses was achieved in 78 % by 3D-TOF and 65% by 3D-PC MRA. |
| doi_str_mv | 10.1007/s002340050645 |
| format | Article |
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On DSA and/or TCD the two observers found 32 and 28 steno-occlusive lesions. 3D-TOF MRA was more sensitive than 3D-PC MRA (87% and 86% vs. 65% and 60%) and had a higher negative predictive value (96% vs. 89%). 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A total of 126 vessels was assessed by PC MRA and 143 by TOF MRA, with digital subtraction angiography (DSA) in 15 patients and/or transcranial Doppler sonography (TCD) in 18 as a standard. Two blinded readers reviewed the MRA, DSA and TCD examinations retrospectively. On DSA and/or TCD the two observers found 32 and 28 steno-occlusive lesions. 3D-TOF MRA was more sensitive than 3D-PC MRA (87% and 86% vs. 65% and 60%) and had a higher negative predictive value (96% vs. 89%). Correct grading of stenoses was achieved in 78 % by 3D-TOF and 65% by 3D-PC MRA.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>9808312</pmid><doi>10.1007/s002340050645</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0028-3940 |
| ispartof | Neuroradiology, 1998-09, Vol.40 (9), p.567-573 |
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| language | eng |
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| source | MEDLINE; SpringerNature Complete Journals |
| subjects | Adult Aged Biological and medical sciences Brain Ischemia - diagnosis Circle of Willis - pathology Female Humans Image Enhancement - instrumentation Image Processing, Computer-Assisted - instrumentation Magnetic Resonance Angiography - instrumentation Male Medical sciences Middle Aged Neurology Observer Variation Sensitivity and Specificity Ultrasonography, Doppler, Transcranial Vascular diseases and vascular malformations of the nervous system |
| title | Intracranial vascular stenosis and occlusion : comparison of 3D time-of-flight and 3D phase-contrast MR angiography |
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