Ion-exchange chromatography separation of the detergent and the solvent from immunoglobulins after solvent–detergent treatment

For inactivation of lipid-enveloped viruses during the immunoglobulin production, the solvent–detergent (S/D) method was applied. Tri-n-butyl phosphate (solvent) and Triton X-100 (detergent) were removed from S/D treated immunoglobulins by ion-exchange chromatography on Q-Sepharose Fast Flow (FF). D...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Chromatography A 1999-08, Vol.852 (1), p.83-86
Hauptverfasser:	Gebauer, B., Šimić, M., Branović, K., Treščec, A., Benko, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biotechnology Chromatography, Ion Exchange - methods Detergents - chemistry Detergents - isolation & purification Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Humans Immunoglobulins Immunoglobulins - chemistry Immunoglobulins - isolation & purification Industrial applications and implications. Economical aspects Monoclonal antibodies Production of active biomolecules Solvents - chemistry Solvents - isolation & purification Tributyl phosphate Triton X-100
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!