Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry

Herpes simplex virus (HSV) has often been suggested as a vector for gene delivery to the nervous system although it is also capable of infecting many other cell types. HSV also has the ability to package large genetic insertions so the expression of multiple genes from a single virus is possible. He...

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Veröffentlicht in:Gene therapy 1998-05, Vol.5 (5), p.718-722
Hauptverfasser: COFFIN, R. S, THOMAS, S. K, CHAIN, B. M, THRASHER, A. T, RUTAULT, K, LATCHMAN, D. S, THOMAS, N. S. B, LILLEY, C. E, PIZZEY, A. R, GRIFFITHS, C. H, GIBB, B. J, WAGSTAFF, M. J. D, INGES, S. J, BINKS, M. H
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