False-Positive Tc-99m Sestamibi Examination for Parathyroid Adenoma in a Case of Asymmetrical Salivary Gland Enlargement

A 50-year-old African American man with multiple endocrine neoplasia type I and Zollinger-Ellison syndrome had a Tc-99m sestamibi scan as part of an evaluation for parathyroid adenoma-hyperplasia. His history was positive for multiple gastric and duodenal ulcers. Biochemical parameters for hyperpara...

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Veröffentlicht in:Clinical nuclear medicine 1999-09, Vol.24 (9), p.723-724
Hauptverfasser: CAMPEAU, RICHARD J, REUTHER, WARREN L, WAYNE, JAMES
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creator CAMPEAU, RICHARD J
REUTHER, WARREN L
WAYNE, JAMES
description A 50-year-old African American man with multiple endocrine neoplasia type I and Zollinger-Ellison syndrome had a Tc-99m sestamibi scan as part of an evaluation for parathyroid adenoma-hyperplasia. His history was positive for multiple gastric and duodenal ulcers. Biochemical parameters for hyperparathyroidism were equivocal; borderline parathyroid hormone elevation was present with low phosphate but normal calcium levels. An abnormal focus of radioactivity was evident in the right neck region in the area of the carotid bifurcation. A CT scan was obtained before contemplated neck exploration. Marked asymmetry of the right submandibular gland, corresponding to the focus of tracer uptake, was present with virtual absence of the left gland. The patient subsequently died of pulmonary embolism on the 25th day after surgery for pancreatic and duodenal neuroendocrine tumors. Post mortem examination confirmed an enlarged right submandibular gland with normal thyroid and parathyroid glands.
doi_str_mv 10.1097/00003072-199909000-00030
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source MEDLINE; Journals@Ovid Complete
subjects Adenoma - diagnostic imaging
Biological and medical sciences
Endocrine glands. Genital system. Mammary gland
Ent. Stomatology
False Positive Reactions
Fatal Outcome
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Parathyroid Neoplasms - diagnostic imaging
Radionuclide Imaging
Radionuclide investigations
Radiopharmaceuticals
Submandibular Gland - abnormalities
Submandibular Gland - diagnostic imaging
Technetium Tc 99m Sestamibi
Tomography, X-Ray Computed
title False-Positive Tc-99m Sestamibi Examination for Parathyroid Adenoma in a Case of Asymmetrical Salivary Gland Enlargement
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