Humoral and cell-mediated responses to Malassezia pachydermatis in healthy dogs and dogs with Malassezia dermatitis
The in vitro proliferative responses of peripheral blood mononuclear cells from seven healthy basset hounds exposed to Malassezia pachydermatis antigen (500 μg/ml) exceeded (P
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| Veröffentlicht in: | Veterinary record 1998-10, Vol.143 (14), p.381-384 |
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| container_issue | 14 |
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| container_title | Veterinary record |
| container_volume | 143 |
| creator | Bond, R. Elwood, C. M. Littler, R. M. Pinter, L. Lloyd, D. H. |
| description | The in vitro proliferative responses of peripheral blood mononuclear cells from seven healthy basset hounds exposed to Malassezia pachydermatis antigen (500 μg/ml) exceeded (P |
| doi_str_mv | 10.1136/vr.143.14.381 |
| format | Article |
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M. ; Littler, R. M. ; Pinter, L. ; Lloyd, D. H.</creator><creatorcontrib>Bond, R. ; Elwood, C. M. ; Littler, R. M. ; Pinter, L. ; Lloyd, D. H.</creatorcontrib><description>The in vitro proliferative responses of peripheral blood mononuclear cells from seven healthy basset hounds exposed to Malassezia pachydermatis antigen (500 μg/ml) exceeded (P<0.05) those of seborrhoeic basset hounds with high populations of M pachydermatis and eight Irish setters with glutensensitive enteropathy. The stimulation indices in the latter two groups and in eight healthy beagles were comparable. The stimulation indices of the four groups after exposure to phytohaemaglutinin did not differ significantly. The serum titres of M pachydermatis-specific IgG and IgA measured by enzymelinked immunosorbent assays (ELISA) in 21 seborrhoeic basset hounds and 11 affected dogs of various breeds exceeded those of 14 healthy basset hounds and eight healthy beagles (P<0.01 for IgG, P<0.05 for IgA). Total serum IgA concentrations measured by ELISA in the affected dogs were not lower than those of healthy dogs.</description><identifier>ISSN: 0042-4900</identifier><identifier>EISSN: 2042-7670</identifier><identifier>DOI: 10.1136/vr.143.14.381</identifier><identifier>PMID: 9802194</identifier><language>eng</language><publisher>England: BMJ Publishing Group Limited</publisher><subject>Animals ; Antibody Formation ; Antigens, Fungal - immunology ; Dermatitis, Seborrheic - immunology ; Dermatitis, Seborrheic - veterinary ; Dermatomycoses - immunology ; Dermatomycoses - veterinary ; Dog Diseases - immunology ; Dogs ; Enzyme-Linked Immunosorbent Assay ; Immunity, Cellular ; Immunoglobulin A - analysis ; Immunoglobulin G - analysis ; Malassezia - immunology</subject><ispartof>Veterinary record, 1998-10, Vol.143 (14), p.381-384</ispartof><rights>British Veterinary Association. All rights reserved.</rights><rights>1998 British Veterinary Association</rights><rights>Copyright: 1998 British Veterinary Association. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b4358-848d849807ae81dac563e9fcf6a1bf376415f6ad2ee28540b48809e9140bfebc3</citedby><cites>FETCH-LOGICAL-b4358-848d849807ae81dac563e9fcf6a1bf376415f6ad2ee28540b48809e9140bfebc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1136%2Fvr.143.14.381$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1136%2Fvr.143.14.381$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9802194$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bond, R.</creatorcontrib><creatorcontrib>Elwood, C. M.</creatorcontrib><creatorcontrib>Littler, R. M.</creatorcontrib><creatorcontrib>Pinter, L.</creatorcontrib><creatorcontrib>Lloyd, D. H.</creatorcontrib><title>Humoral and cell-mediated responses to Malassezia pachydermatis in healthy dogs and dogs with Malassezia dermatitis</title><title>Veterinary record</title><addtitle>Vet Rec</addtitle><description>The in vitro proliferative responses of peripheral blood mononuclear cells from seven healthy basset hounds exposed to Malassezia pachydermatis antigen (500 μg/ml) exceeded (P<0.05) those of seborrhoeic basset hounds with high populations of M pachydermatis and eight Irish setters with glutensensitive enteropathy. The stimulation indices in the latter two groups and in eight healthy beagles were comparable. The stimulation indices of the four groups after exposure to phytohaemaglutinin did not differ significantly. The serum titres of M pachydermatis-specific IgG and IgA measured by enzymelinked immunosorbent assays (ELISA) in 21 seborrhoeic basset hounds and 11 affected dogs of various breeds exceeded those of 14 healthy basset hounds and eight healthy beagles (P<0.01 for IgG, P<0.05 for IgA). Total serum IgA concentrations measured by ELISA in the affected dogs were not lower than those of healthy dogs.</description><subject>Animals</subject><subject>Antibody Formation</subject><subject>Antigens, Fungal - immunology</subject><subject>Dermatitis, Seborrheic - immunology</subject><subject>Dermatitis, Seborrheic - veterinary</subject><subject>Dermatomycoses - immunology</subject><subject>Dermatomycoses - veterinary</subject><subject>Dog Diseases - immunology</subject><subject>Dogs</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Immunity, Cellular</subject><subject>Immunoglobulin A - analysis</subject><subject>Immunoglobulin G - analysis</subject><subject>Malassezia - immunology</subject><issn>0042-4900</issn><issn>2042-7670</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFUctKxEAQHETR9XH0KAwI4iXrvJJMjrr4AkUQ9TpMko6bJY91JlmJX2-vu4h40EMzBV1V1FQTcsjZmHMZnS3cmCuJM5aab5CRYEoEcRSzTTJiS6wSxnbIrvczxkQSSrFNthPNBE_UiPibvm6drahtcppBVQU15KXtIKcO_LxtPHjatfTeVtZ7-CgtndtsOuTgatuVnpYNnYKtuulA8_bVf_l8gfeym_6UrRWo2Sdbha08HKzfPfJ8dfk0uQnuHq5vJ-d3QapkqAOtdK4VJo0taJ7bLIwkJEVWRJanhYwjxUPEuQAQOlQsVVqzBBKOsIA0k3vkZOU7d-1bD74zdemXf7QNtL03MfYhI8GRePyLOGt712A2w-NYYM1SMmQFK1bmWu8dFGbuytq6wXBmlqcwC2fwFDgGT4H8o7Vrn2Kp3-x197iPVvv3soLhbzPzcvn0eHElokRqFJ6uhGk9-yfDJ9keopg</recordid><startdate>19981003</startdate><enddate>19981003</enddate><creator>Bond, R.</creator><creator>Elwood, C. 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M.</au><au>Littler, R. M.</au><au>Pinter, L.</au><au>Lloyd, D. H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Humoral and cell-mediated responses to Malassezia pachydermatis in healthy dogs and dogs with Malassezia dermatitis</atitle><jtitle>Veterinary record</jtitle><addtitle>Vet Rec</addtitle><date>1998-10-03</date><risdate>1998</risdate><volume>143</volume><issue>14</issue><spage>381</spage><epage>384</epage><pages>381-384</pages><issn>0042-4900</issn><eissn>2042-7670</eissn><abstract>The in vitro proliferative responses of peripheral blood mononuclear cells from seven healthy basset hounds exposed to Malassezia pachydermatis antigen (500 μg/ml) exceeded (P<0.05) those of seborrhoeic basset hounds with high populations of M pachydermatis and eight Irish setters with glutensensitive enteropathy. The stimulation indices in the latter two groups and in eight healthy beagles were comparable. The stimulation indices of the four groups after exposure to phytohaemaglutinin did not differ significantly. The serum titres of M pachydermatis-specific IgG and IgA measured by enzymelinked immunosorbent assays (ELISA) in 21 seborrhoeic basset hounds and 11 affected dogs of various breeds exceeded those of 14 healthy basset hounds and eight healthy beagles (P<0.01 for IgG, P<0.05 for IgA). Total serum IgA concentrations measured by ELISA in the affected dogs were not lower than those of healthy dogs.</abstract><cop>England</cop><pub>BMJ Publishing Group Limited</pub><pmid>9802194</pmid><doi>10.1136/vr.143.14.381</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Veterinary record, 1998-10, Vol.143 (14), p.381-384 |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Animals Antibody Formation Antigens, Fungal - immunology Dermatitis, Seborrheic - immunology Dermatitis, Seborrheic - veterinary Dermatomycoses - immunology Dermatomycoses - veterinary Dog Diseases - immunology Dogs Enzyme-Linked Immunosorbent Assay Immunity, Cellular Immunoglobulin A - analysis Immunoglobulin G - analysis Malassezia - immunology |
| title | Humoral and cell-mediated responses to Malassezia pachydermatis in healthy dogs and dogs with Malassezia dermatitis |
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