The use of lamotrigine in neuropathic pain
Sodium channel antagonists have been used in the management of neuropathic pain for several years. Recent evidence suggests that lamotrigine, which is active at glutaminergic excitatory synapses, is very effective in producing pain relief. We have successfully used lamotrigine in two patients suffer...
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| Veröffentlicht in: | Anaesthesia 1998-08, Vol.53 (8), p.808-809 |
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| container_title | Anaesthesia |
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| creator | Di Vadi, P. P. Hamann, W. |
| description | Sodium channel antagonists have been used in the management of neuropathic pain for several years. Recent evidence suggests that lamotrigine, which is active at glutaminergic excitatory synapses, is very effective in producing pain relief. We have successfully used lamotrigine in two patients suffering from neuropathic pain. Our results suggest that this novel channel antagonist can be used to treat neuropathic pain. Double blind placebo control studies are therefore needed to substantiate these findings. |
| doi_str_mv | 10.1046/j.1365-2044.1998.00564.x |
| format | Article |
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Double blind placebo control studies are therefore needed to substantiate these findings.</description><identifier>ISSN: 0003-2409</identifier><identifier>EISSN: 1365-2044</identifier><identifier>DOI: 10.1046/j.1365-2044.1998.00564.x</identifier><identifier>PMID: 9797526</identifier><identifier>CODEN: ANASAB</identifier><language>eng</language><publisher>Oxford: Blackwell Science Ltd</publisher><subject>Analgesics ; Analgesics - therapeutic use ; Biological and medical sciences ; Humans ; Lamotrigine ; Male ; Medical sciences ; Middle Aged ; Neuralgia - drug therapy ; Neuropharmacology ; Pain; pathological ; Pharmacology. 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Double blind placebo control studies are therefore needed to substantiate these findings.</description><subject>Analgesics</subject><subject>Analgesics - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Humans</subject><subject>Lamotrigine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neuralgia - drug therapy</subject><subject>Neuropharmacology</subject><subject>Pain; pathological</subject><subject>Pharmacology. 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| ispartof | Anaesthesia, 1998-08, Vol.53 (8), p.808-809 |
| issn | 0003-2409 1365-2044 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Free Content |
| subjects | Analgesics Analgesics - therapeutic use Biological and medical sciences Humans Lamotrigine Male Medical sciences Middle Aged Neuralgia - drug therapy Neuropharmacology Pain pathological Pharmacology. Drug treatments Pharmacology lamotrigine Sodium Channel Blockers Triazines - therapeutic use |
| title | The use of lamotrigine in neuropathic pain |
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