The CD8+ Cell Phenotype Mediating Antiviral Activity in Feline Immunodeficiency Virus—Infected Cats Is Characterized by Reduced Surface Expression of the CD8 β Chain

The acute stage of feline immunodeficiency virus (FIV) infection is characterized by a CD8+ anti-FIV response that parallels the appearance of a CD8+ subpopulation with reduced expression of the β chain (CD8α+βlo). The relationship between the CD8α+βlo phenotype and CD8+ anti-FIV activity was examin...

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Veröffentlicht in:	The Journal of infectious diseases 1998-10, Vol.178 (4), p.968-977
Hauptverfasser:	Bucci, Joseph G., Gebhard, Douglas H., Childers, Tedd A., English, Robert V., Tompkins, Mary B., Tompkins, Wayne A. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease AIDS/HIV Analysis of the immune response. Humoral and cellular immunity Animals Antibody Specificity Antivirals Biological and medical sciences Carrier State Cats CD8 Antigens - biosynthesis CD8 Antigens - immunology CD8-Positive T-Lymphocytes - immunology Down-Regulation Feline Acquired Immunodeficiency Syndrome - immunology Flow Cytometry Fundamental and applied biological sciences. Psychology Fundamental immunology HIV Immunity, Cellular Immunobiology Immunodeficiency Virus, Feline - isolation & purification Infections Lymphocytes Major Articles Monoclonal antibodies Organs and cells involved in the immune response Phenotype Phenotypes Physiological immunosuppression T lymphocytes Viruses
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