A Dominant Role for the Thymus and MHC Genes in Determining the Peripheral CD4/CD8 T Cell Ratio in the Rat

During their development, immature CD4CD8 double positive thymocytes become committed to either the CD4 or CD8 lineage. The final size of the peripheral CD4 and CD8 T cell compartments depends on thymic output and on the differential survival and proliferation of the respective T cell subsets in the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 1999-09, Vol.163 (6), p.2983-2989
Hauptverfasser:	Damoiseaux, Jan G. M. C, Cautain, Bastien, Bernard, Isabelle, Mas, Magali, van Breda Vriesman, Peter J. C, Druet, Philippe, Fournie, Gilbert, Saoudi, Abdelhadi
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals CD4-CD8 Ratio CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism CD8 Antigens - biosynthesis CD8-Positive T-Lymphocytes - cytology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Epithelial Cells - immunology Epithelial Cells - metabolism Female Haplotypes Hematopoietic Stem Cells - immunology Hematopoietic Stem Cells - metabolism Lymphocyte Activation Lymphocyte Count Major Histocompatibility Complex - genetics Male Radiation Chimera - immunology Rats Rats, Inbred BN Rats, Inbred Lew Stromal Cells - immunology Stromal Cells - metabolism Thymus Gland - cytology Thymus Gland - immunology Thymus Gland - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!