Effects of glycosylation on fragments of tumour associated human epithelial mucin MUC1

The glycodecapeptide AcPAPGS(alpha GalNAc)T(alpha GalNAc)APPA and the C-terminal glycohexapeptide AcS(alpha GalNAc)T(alpha GalNAc)APPA have been synthesized by applying the N-terminal Fmoc group in combination with the heptyl ester cleavable by lipase-catalyzed hydrolysis at pH 7. The solution confo...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 1998-09, Vol.6 (9), p.1531-1545
Hauptverfasser:	Braun, P, Davies, G M, Price, M R, Williams, P M, Tendler, S J, Kunz, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Glycosylation Humans Magnetic Resonance Spectroscopy Models, Molecular Molecular Sequence Data Mucin-1 - chemistry Mucin-1 - metabolism Peptide Fragments - metabolism Protein Conformation Spectrometry, Mass, Fast Atom Bombardment
Online-Zugang:	Volltext
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