Hyporesponsiveness of peripheral blood lymphocytes to streptococcal superantigens in patients with guttate psoriasis : Evidence for systemic stimulation of T cells with superantigens released from focally infecting Streptococcus pyogenes

Throat infection with Streptococcus pyogenes is the most important trigger for acute guttate psoriasis. We examined the in vitro responses of peripheral blood mononuclear cells (PBMC) to streptococcal superantigens, SPEA and SPEC, and staphylococcal superantigens, SEB and TSST-1, in patients with gu...

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Veröffentlicht in:	Archives of Dermatological Research 1999-07, Vol.291 (7-8), p.382-389
Hauptverfasser:	TOKURA, Y, SEO, N, OHSHIMA, A, WAKITA, H, YOKOTE, R, FURUKAWA, F, TAKIGAWA, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens, Bacterial - immunology Biological and medical sciences Dermatology Female Humans Lymphocyte Activation Lymphocytes - immunology Male Medical sciences Middle Aged Psoriasis - immunology Psoriasis - microbiology Psoriasis - pathology Psoriasis. Parapsoriasis. Lichen Staphylococcus - immunology Streptococcal Infections - immunology Streptococcus pyogenes - immunology Superantigens - immunology T-Lymphocytes - immunology
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