The c-erbB-2 Oncogene Amplification by Competitive PCR in Aneuploid Cell Clones Flow Sorted from Breast Cancer Samples

The amplification of c-erbB-2 oncogene has been reported to have clinical relevance as a prognostic index in breast cancer. However, controversies still remain about its interpretation, mainly due to the inaccuracy of methods used for this purpose and to the unpredictable variability of the ratio be...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 1999-06, Vol.37 (6), p.649-654
Hauptverfasser:	Vona, Giovanna, Caldini, Anna, Sestini, Roberta, Rapi, Stefano, Bianchi, Simonetta, Fanelli, Alessandra, Pazzagli, Mario, Orlando, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Biological and medical sciences Breast Neoplasms - genetics Breast Neoplasms - pathology Clone Cells Gene Amplification Genes, erbB-2 Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Polymerase Chain Reaction - methods Prognosis Tumors
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