Expression of Trypanosoma cruzi surface antigen FL-160 is controlled by elements in the 3′ untranslated, the 3′ intergenic, and the coding regions

The FL-160 surface antigen gene family of T. cruzi consists of hundreds of members of 160 kDa glycoproteins expressed in trypomastigotes, but not in epimastigotes. Steady-state levels of FL-160 mRNA were 80 to 100-fold higher in trypomastigotes than in epimastigotes, yet transcription rates were equ...

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Veröffentlicht in:	Molecular and biochemical parasitology 1999-07, Vol.102 (1), p.53-66
Hauptverfasser:	Weston, David, La Flamme, Anne C., Van Voorhis, Wesley C.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics Animals Antigens, Protozoan - biosynthesis Antigens, Protozoan - genetics Base Sequence Blotting, Southern DNA, Protozoan - genetics Gene expression Gene Expression Regulation Genes, Protozoan Molecular Sequence Data RNA stability RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Protozoan - genetics Sequence Analysis, DNA Surface antigens Transcription, Genetic Trypanosoma cruzi Trypanosoma cruzi - genetics Trypanosoma cruzi - growth & development Trypanosoma cruzi - immunology
Online-Zugang:	Volltext
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