Simultaneous determination of diclofenac and oxybuprocaine in human aqueous humor with HPLC and electrochemical detection

A sensitive and selective bioanalytical method for simultaneous determination of diclofenac and oxybuprocaine in human aqueous humor using reversed-phase HPLC and electrochemical detection is described. Chromatographic separation was achieved by using a Regis SPS 100 RP-8 column (5 μm; 150×4.6 mm I....

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 1998-09, Vol.17 (8), p.1351-1356
Hauptverfasser:	Kuhlmann, Olaf, Stoldt, Gundula, Struck, Hans-Gert, Krauss, Gerd-Joachim
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anesthetics, Local - analysis Aqueous Humor - chemistry Biological and medical sciences Cataract Extraction Chromatography, High Pressure Liquid - methods Cyclooxygenase Inhibitors - analysis Diclofenac Diclofenac - analysis Electrochemical detection Electrochemistry - methods General pharmacology Human aqueous humor Humans Medical sciences Oxybuprocaine Pharmacology. Drug treatments Procaine - analogs & derivatives Procaine - analysis Reversed-phase high-performance liquid chromatography Sensitivity and Specificity
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