Activity of GH/IGF-I axis in patients with dilated cardiomyopathy

OBJECTIVE There is evidence showing that GH and IGF‐I have specific receptors in the heart and that these hormones are able to promote cardiac remodelling and inotropism. It has been reported that patients with dilated cardiomyopathy (DCM) benefit from treatment with rhGH showing a striking increase...

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Veröffentlicht in:	Clinical endocrinology (Oxford) 1999-04, Vol.50 (4), p.417-430
Hauptverfasser:	Broglio, Fabio, Fubini, Alberto, Morello, Mara, Arvat, Emanuela, Aimaretti, Gianluca, Gianotti, Laura, Boghen, Muny F., Deghenghi, Romano, Mangiardi, Lucia, Ghigo, Ezio
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiomyopathy, Dilated - drug therapy Cardiomyopathy, Dilated - metabolism Cardiomyopathy, Dilated - physiopathology Case-Control Studies Female Growth Hormone - blood Growth Hormone - metabolism Growth Hormone - therapeutic use Growth Hormone-Releasing Hormone Humans Insulin-Like Growth Factor I - analysis Insulin-Like Growth Factor I - metabolism Male Middle Aged Oligopeptides
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