Association of increased CD4+ T-cell infiltration with increased IL-16 gene expression in atopic dermatitis

Background: The mechanisms involved in the initiation and the maintenance of skin inflammation in atopic dermatitis (AD) are poorly understood. Previous studies have demonstrated increased numbers of infiltrating CD4 + T cells in acute lesions compared with normal control skin. IL-16 is a cytokine t...

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Veröffentlicht in:	Journal of allergy and clinical immunology 1998-10, Vol.102 (4), p.645-650
Hauptverfasser:	Laberge, Sophie, Ghaffar, Omar, Boguniewicz, Mark, Center, David M., Leung, Donald Y.M., Hamid, Qutayba
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases allergic inflammation Atopic dermatitis Biological and medical sciences Biopsy CD4-Positive T-Lymphocytes - immunology chemotaxis Dermatitis, Atopic - genetics Dermatitis, Atopic - immunology Gene Expression Humans IL-16 Immunohistochemistry Immunopathology In Situ Hybridization Interleukin-16 - genetics Medical sciences RNA, Messenger - metabolism Skin - immunology Skin - pathology Skin allergic diseases. Stinging insect allergies
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