BID, a Proapoptotic BCL-2 Family Member, Is Localized to Mouse Chromosome 6 and Human Chromosome 22q11
BID is a proapoptotic member of the BCL-2 family of cell death regulators. BID shares sequence homology with other members of the family within a single α-helical domain, BH3. BH3 is required for BID to interact with BCL-2 and BAX, as well as for its function as a death agonist. We have isolated and...
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| Veröffentlicht in: | Genomics (San Diego, Calif.) Calif.), 1998-10, Vol.53 (2), p.235-238 |
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| container_title | Genomics (San Diego, Calif.) |
| container_volume | 53 |
| creator | Wang, Kun Yin, Xiao-Ming Copeland, Neal G. Gilbert, Debra J. Jenkins, Nancy A. Keck, Catherine L. Zimonjic, Drazen B. Popescu, Nicholas C. Korsmeyer, Stanley J. |
| description | BID is a proapoptotic member of the BCL-2 family of cell death regulators. BID shares sequence homology with other members of the family within a single α-helical domain, BH3. BH3 is required for BID to interact with BCL-2 and BAX, as well as for its function as a death agonist. We have isolated and characterized mouseBidand humanBIDgenomic clones. The sequence for BID is encoded within five exons. We used interspecific backcross analysis to localizeBidto the distal region of mouse chromosome 6 near theAtp6elocus. Fluorescencein situhybridization analysis localized humanBIDto a syntenic human region, chromosome 22q11, close to theBCR-1gene. |
| doi_str_mv | 10.1006/geno.1998.5489 |
| format | Article |
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BID shares sequence homology with other members of the family within a single α-helical domain, BH3. BH3 is required for BID to interact with BCL-2 and BAX, as well as for its function as a death agonist. We have isolated and characterized mouseBidand humanBIDgenomic clones. The sequence for BID is encoded within five exons. We used interspecific backcross analysis to localizeBidto the distal region of mouse chromosome 6 near theAtp6elocus. Fluorescencein situhybridization analysis localized humanBIDto a syntenic human region, chromosome 22q11, close to theBCR-1gene.</description><identifier>ISSN: 0888-7543</identifier><identifier>EISSN: 1089-8646</identifier><identifier>DOI: 10.1006/geno.1998.5489</identifier><identifier>PMID: 9790773</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>Animals ; BH3 Interacting Domain Death Agonist Protein ; Biological and medical sciences ; Carrier Proteins - genetics ; Chromosome Mapping ; Chromosomes, Human, Pair 22 ; Classical genetics, quantitative genetics, hybrids ; Exons ; Fundamental and applied biological sciences. Psychology ; Genetics of eukaryotes. Biological and molecular evolution ; Human ; Humans ; In Situ Hybridization, Fluorescence ; Introns ; Mice ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Molecular Sequence Data</subject><ispartof>Genomics (San Diego, Calif.), 1998-10, Vol.53 (2), p.235-238</ispartof><rights>1998 Academic Press</rights><rights>1999 INIST-CNRS</rights><rights>Copyright 1998 Academic Press.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c399t-848d6d2e2a91af763155d6bf6988769609ded14903a85922ddf7c600482978023</citedby><cites>FETCH-LOGICAL-c399t-848d6d2e2a91af763155d6bf6988769609ded14903a85922ddf7c600482978023</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1006/geno.1998.5489$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1590651$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9790773$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Kun</creatorcontrib><creatorcontrib>Yin, Xiao-Ming</creatorcontrib><creatorcontrib>Copeland, Neal G.</creatorcontrib><creatorcontrib>Gilbert, Debra J.</creatorcontrib><creatorcontrib>Jenkins, Nancy A.</creatorcontrib><creatorcontrib>Keck, Catherine L.</creatorcontrib><creatorcontrib>Zimonjic, Drazen B.</creatorcontrib><creatorcontrib>Popescu, Nicholas C.</creatorcontrib><creatorcontrib>Korsmeyer, Stanley J.</creatorcontrib><title>BID, a Proapoptotic BCL-2 Family Member, Is Localized to Mouse Chromosome 6 and Human Chromosome 22q11</title><title>Genomics (San Diego, Calif.)</title><addtitle>Genomics</addtitle><description>BID is a proapoptotic member of the BCL-2 family of cell death regulators. BID shares sequence homology with other members of the family within a single α-helical domain, BH3. BH3 is required for BID to interact with BCL-2 and BAX, as well as for its function as a death agonist. We have isolated and characterized mouseBidand humanBIDgenomic clones. The sequence for BID is encoded within five exons. We used interspecific backcross analysis to localizeBidto the distal region of mouse chromosome 6 near theAtp6elocus. Fluorescencein situhybridization analysis localized humanBIDto a syntenic human region, chromosome 22q11, close to theBCR-1gene.</description><subject>Animals</subject><subject>BH3 Interacting Domain Death Agonist Protein</subject><subject>Biological and medical sciences</subject><subject>Carrier Proteins - genetics</subject><subject>Chromosome Mapping</subject><subject>Chromosomes, Human, Pair 22</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>Exons</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>Human</subject><subject>Humans</subject><subject>In Situ Hybridization, Fluorescence</subject><subject>Introns</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>Mice, Inbred Strains</subject><subject>Molecular Sequence Data</subject><issn>0888-7543</issn><issn>1089-8646</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFvEzEQhS0EKmnhyg3JB8SpG8beXdtzpIHSSKngAGfLsWfBaHed2ptK5dezUaLCBXEaaeabN6P3GHslYCkA1LvvNKalQDTLtjH4hC0EGKyMatRTtgBjTKXbpn7Ozkv5CQBYG3nGzlAjaF0vWHe1_nDJHf-Sk9ul3ZSm6PnValNJfu2G2D_wWxq2lC_5uvBN8q6PvyjwKfHbtC_EVz9yGlJJA3HF3Rj4zX5w499tKe-EeMGeda4v9PJUL9i3649fVzfV5vOn9er9pvI14lSZxgQVJEmHwnVa1aJtg9p2Co3RChVgoCAahNqZFqUModNeATRGojYg6wv29qi7y-luT2WyQyye-t6NNP9rNYBooG3_CwoNOJ-oZ3B5BH1OpWTq7C7HweUHK8AeErCHBOwhAXtIYF54fVLebwcKj_jJ8nn-5jR3Zbazy270sfxRbRFUK2bMHDGa7bqPlG3xkUZPIWbykw0p_uuD327Lneg</recordid><startdate>19981015</startdate><enddate>19981015</enddate><creator>Wang, Kun</creator><creator>Yin, Xiao-Ming</creator><creator>Copeland, Neal G.</creator><creator>Gilbert, Debra J.</creator><creator>Jenkins, Nancy A.</creator><creator>Keck, Catherine L.</creator><creator>Zimonjic, Drazen B.</creator><creator>Popescu, Nicholas C.</creator><creator>Korsmeyer, Stanley J.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19981015</creationdate><title>BID, a Proapoptotic BCL-2 Family Member, Is Localized to Mouse Chromosome 6 and Human Chromosome 22q11</title><author>Wang, Kun ; Yin, Xiao-Ming ; Copeland, Neal G. ; Gilbert, Debra J. ; Jenkins, Nancy A. ; Keck, Catherine L. ; Zimonjic, Drazen B. ; Popescu, Nicholas C. ; Korsmeyer, Stanley J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c399t-848d6d2e2a91af763155d6bf6988769609ded14903a85922ddf7c600482978023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Animals</topic><topic>BH3 Interacting Domain Death Agonist Protein</topic><topic>Biological and medical sciences</topic><topic>Carrier Proteins - genetics</topic><topic>Chromosome Mapping</topic><topic>Chromosomes, Human, Pair 22</topic><topic>Classical genetics, quantitative genetics, hybrids</topic><topic>Exons</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genetics of eukaryotes. Biological and molecular evolution</topic><topic>Human</topic><topic>Humans</topic><topic>In Situ Hybridization, Fluorescence</topic><topic>Introns</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>Mice, Inbred Strains</topic><topic>Molecular Sequence Data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Kun</creatorcontrib><creatorcontrib>Yin, Xiao-Ming</creatorcontrib><creatorcontrib>Copeland, Neal G.</creatorcontrib><creatorcontrib>Gilbert, Debra J.</creatorcontrib><creatorcontrib>Jenkins, Nancy A.</creatorcontrib><creatorcontrib>Keck, Catherine L.</creatorcontrib><creatorcontrib>Zimonjic, Drazen B.</creatorcontrib><creatorcontrib>Popescu, Nicholas C.</creatorcontrib><creatorcontrib>Korsmeyer, Stanley J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Genomics (San Diego, Calif.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Kun</au><au>Yin, Xiao-Ming</au><au>Copeland, Neal G.</au><au>Gilbert, Debra J.</au><au>Jenkins, Nancy A.</au><au>Keck, Catherine L.</au><au>Zimonjic, Drazen B.</au><au>Popescu, Nicholas C.</au><au>Korsmeyer, Stanley J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>BID, a Proapoptotic BCL-2 Family Member, Is Localized to Mouse Chromosome 6 and Human Chromosome 22q11</atitle><jtitle>Genomics (San Diego, Calif.)</jtitle><addtitle>Genomics</addtitle><date>1998-10-15</date><risdate>1998</risdate><volume>53</volume><issue>2</issue><spage>235</spage><epage>238</epage><pages>235-238</pages><issn>0888-7543</issn><eissn>1089-8646</eissn><abstract>BID is a proapoptotic member of the BCL-2 family of cell death regulators. BID shares sequence homology with other members of the family within a single α-helical domain, BH3. BH3 is required for BID to interact with BCL-2 and BAX, as well as for its function as a death agonist. We have isolated and characterized mouseBidand humanBIDgenomic clones. The sequence for BID is encoded within five exons. We used interspecific backcross analysis to localizeBidto the distal region of mouse chromosome 6 near theAtp6elocus. Fluorescencein situhybridization analysis localized humanBIDto a syntenic human region, chromosome 22q11, close to theBCR-1gene.</abstract><cop>San Diego, CA</cop><pub>Elsevier Inc</pub><pmid>9790773</pmid><doi>10.1006/geno.1998.5489</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals BH3 Interacting Domain Death Agonist Protein Biological and medical sciences Carrier Proteins - genetics Chromosome Mapping Chromosomes, Human, Pair 22 Classical genetics, quantitative genetics, hybrids Exons Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Human Humans In Situ Hybridization, Fluorescence Introns Mice Mice, Inbred C57BL Mice, Inbred Strains Molecular Sequence Data |
| title | BID, a Proapoptotic BCL-2 Family Member, Is Localized to Mouse Chromosome 6 and Human Chromosome 22q11 |
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