Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer
We report a case of Alcaligenes xylosoxidans keratitis following penetrating keratoplasty in a rigid gas permeable (RGP) lens wearer. A 61 year old RGP lens wearer with a history of nonresponsive keratitis of the right eye which involved the graft margin was referred to us for treatment. Corneal cul...
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| Veröffentlicht in: | The CLAO journal 1998-10, Vol.24 (4), p.239-241 |
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| creator | LIN, A DRIEBE, W. T POLACK, P |
| description | We report a case of Alcaligenes xylosoxidans keratitis following penetrating keratoplasty in a rigid gas permeable (RGP) lens wearer.
A 61 year old RGP lens wearer with a history of nonresponsive keratitis of the right eye which involved the graft margin was referred to us for treatment. Corneal cultures revealed growth of a gram-negative rod on the fifth day and the organism was subsequently identified as Alcaligenes xylosoxidans, which was resistant to most antibiotics and sensitive only to Bactrim, Timentin, and imipenem.
Clinical improvement was observed within 24 hours after treatment with the use of topical i.v. Bactrim and topical i.v. Timentin 2% alternating every 30 minutes. Complete resolution of the infection with mild scarring was observed 6 weeks after treatment.
Alcaligenes xylosoxidans is a potential cause of bacterial keratitis which should be considered in cases of nonresponsive gram-negative keratitis. The addition of topical Bactrim or Timentin may need to be considered in such cases. |
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A 61 year old RGP lens wearer with a history of nonresponsive keratitis of the right eye which involved the graft margin was referred to us for treatment. Corneal cultures revealed growth of a gram-negative rod on the fifth day and the organism was subsequently identified as Alcaligenes xylosoxidans, which was resistant to most antibiotics and sensitive only to Bactrim, Timentin, and imipenem.
Clinical improvement was observed within 24 hours after treatment with the use of topical i.v. Bactrim and topical i.v. Timentin 2% alternating every 30 minutes. Complete resolution of the infection with mild scarring was observed 6 weeks after treatment.
Alcaligenes xylosoxidans is a potential cause of bacterial keratitis which should be considered in cases of nonresponsive gram-negative keratitis. The addition of topical Bactrim or Timentin may need to be considered in such cases.</description><identifier>ISSN: 0733-8902</identifier><identifier>EISSN: 1538-0181</identifier><identifier>PMID: 9800065</identifier><identifier>CODEN: CLAJEU</identifier><language>eng</language><publisher>New York, NY: Kellner/McCaffery</publisher><subject><![CDATA[Administration, Topical ; Alcaligenes - isolation & purification ; Anti-Bacterial Agents - administration & dosage ; Anti-Bacterial Agents - therapeutic use ; Bacterial Infections - drug therapy ; Bacterial Infections - etiology ; Bacterial Infections - microbiology ; Biological and medical sciences ; Clavulanic Acids - administration & dosage ; Clavulanic Acids - therapeutic use ; Contact Lenses ; Cornea - microbiology ; Drug Therapy, Combination - administration & dosage ; Drug Therapy, Combination - therapeutic use ; Gases ; Humans ; Keratitis - etiology ; Keratitis - microbiology ; Keratoplasty, Penetrating ; Male ; Medical sciences ; Middle Aged ; Permeability ; Postoperative Complications ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the eye and orbit ; Ticarcillin - administration & dosage ; Ticarcillin - therapeutic use ; Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage ; Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use]]></subject><ispartof>The CLAO journal, 1998-10, Vol.24 (4), p.239-241</ispartof><rights>1999 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1580936$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9800065$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LIN, A</creatorcontrib><creatorcontrib>DRIEBE, W. T</creatorcontrib><creatorcontrib>POLACK, P</creatorcontrib><title>Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer</title><title>The CLAO journal</title><addtitle>CLAO J</addtitle><description>We report a case of Alcaligenes xylosoxidans keratitis following penetrating keratoplasty in a rigid gas permeable (RGP) lens wearer.
A 61 year old RGP lens wearer with a history of nonresponsive keratitis of the right eye which involved the graft margin was referred to us for treatment. Corneal cultures revealed growth of a gram-negative rod on the fifth day and the organism was subsequently identified as Alcaligenes xylosoxidans, which was resistant to most antibiotics and sensitive only to Bactrim, Timentin, and imipenem.
Clinical improvement was observed within 24 hours after treatment with the use of topical i.v. Bactrim and topical i.v. Timentin 2% alternating every 30 minutes. Complete resolution of the infection with mild scarring was observed 6 weeks after treatment.
Alcaligenes xylosoxidans is a potential cause of bacterial keratitis which should be considered in cases of nonresponsive gram-negative keratitis. The addition of topical Bactrim or Timentin may need to be considered in such cases.</description><subject>Administration, Topical</subject><subject>Alcaligenes - isolation & purification</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bacterial Infections - drug therapy</subject><subject>Bacterial Infections - etiology</subject><subject>Bacterial Infections - microbiology</subject><subject>Biological and medical sciences</subject><subject>Clavulanic Acids - administration & dosage</subject><subject>Clavulanic Acids - therapeutic use</subject><subject>Contact Lenses</subject><subject>Cornea - microbiology</subject><subject>Drug Therapy, Combination - administration & dosage</subject><subject>Drug Therapy, Combination - therapeutic use</subject><subject>Gases</subject><subject>Humans</subject><subject>Keratitis - etiology</subject><subject>Keratitis - microbiology</subject><subject>Keratoplasty, Penetrating</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Permeability</subject><subject>Postoperative Complications</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the eye and orbit</subject><subject>Ticarcillin - administration & dosage</subject><subject>Ticarcillin - therapeutic use</subject><subject>Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage</subject><subject>Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use</subject><issn>0733-8902</issn><issn>1538-0181</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1LxDAURYMo4zj6E4QsxF3hpbVpshwGv2DAja7La_Jaopm2Jh2c-fdGpshbXHjncBf3jC1FWagMhBLnbAlVUWRKQ37JrmL8BMjTVQu20AoAZLlktPYGveuop8gPRz_E4eAs9pF_UcDJTS7ycYgTH5Mx_X367oSG0WOcjtz1HHlwnbO8wyRT2BE2nrin1PJDGChcs4sWfaSbOVfs4-nxffOSbd-eXzfrbTaKEqbMmNzIVj2UVjRSKlFKDVVLaLUEkxe50cJaqVVuhaGmEkRGyAYb1KasQGCxYven3jEM33uKU71z0ZD32NOwj3UFIPI0RxJvZ3Hf7MjWY3A7DMd63iXxu5ljTPu0AXvj4r8mSgW6kMUvduRuyw</recordid><startdate>199810</startdate><enddate>199810</enddate><creator>LIN, A</creator><creator>DRIEBE, W. T</creator><creator>POLACK, P</creator><general>Kellner/McCaffery</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199810</creationdate><title>Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer</title><author>LIN, A ; DRIEBE, W. T ; POLACK, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p150t-cc2c6f845d1b668156907fead960c232c91dd6982d1ceb71eec16baba9c5701a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Administration, Topical</topic><topic>Alcaligenes - isolation & purification</topic><topic>Anti-Bacterial Agents - administration & dosage</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Bacterial Infections - drug therapy</topic><topic>Bacterial Infections - etiology</topic><topic>Bacterial Infections - microbiology</topic><topic>Biological and medical sciences</topic><topic>Clavulanic Acids - administration & dosage</topic><topic>Clavulanic Acids - therapeutic use</topic><topic>Contact Lenses</topic><topic>Cornea - microbiology</topic><topic>Drug Therapy, Combination - administration & dosage</topic><topic>Drug Therapy, Combination - therapeutic use</topic><topic>Gases</topic><topic>Humans</topic><topic>Keratitis - etiology</topic><topic>Keratitis - microbiology</topic><topic>Keratoplasty, Penetrating</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Permeability</topic><topic>Postoperative Complications</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the eye and orbit</topic><topic>Ticarcillin - administration & dosage</topic><topic>Ticarcillin - therapeutic use</topic><topic>Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage</topic><topic>Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use</topic><toplevel>online_resources</toplevel><creatorcontrib>LIN, A</creatorcontrib><creatorcontrib>DRIEBE, W. T</creatorcontrib><creatorcontrib>POLACK, P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The CLAO journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LIN, A</au><au>DRIEBE, W. T</au><au>POLACK, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer</atitle><jtitle>The CLAO journal</jtitle><addtitle>CLAO J</addtitle><date>1998-10</date><risdate>1998</risdate><volume>24</volume><issue>4</issue><spage>239</spage><epage>241</epage><pages>239-241</pages><issn>0733-8902</issn><eissn>1538-0181</eissn><coden>CLAJEU</coden><abstract>We report a case of Alcaligenes xylosoxidans keratitis following penetrating keratoplasty in a rigid gas permeable (RGP) lens wearer.
A 61 year old RGP lens wearer with a history of nonresponsive keratitis of the right eye which involved the graft margin was referred to us for treatment. Corneal cultures revealed growth of a gram-negative rod on the fifth day and the organism was subsequently identified as Alcaligenes xylosoxidans, which was resistant to most antibiotics and sensitive only to Bactrim, Timentin, and imipenem.
Clinical improvement was observed within 24 hours after treatment with the use of topical i.v. Bactrim and topical i.v. Timentin 2% alternating every 30 minutes. Complete resolution of the infection with mild scarring was observed 6 weeks after treatment.
Alcaligenes xylosoxidans is a potential cause of bacterial keratitis which should be considered in cases of nonresponsive gram-negative keratitis. The addition of topical Bactrim or Timentin may need to be considered in such cases.</abstract><cop>New York, NY</cop><pub>Kellner/McCaffery</pub><pmid>9800065</pmid><tpages>3</tpages></addata></record> |
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| ispartof | The CLAO journal, 1998-10, Vol.24 (4), p.239-241 |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Administration, Topical Alcaligenes - isolation & purification Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Bacterial Infections - drug therapy Bacterial Infections - etiology Bacterial Infections - microbiology Biological and medical sciences Clavulanic Acids - administration & dosage Clavulanic Acids - therapeutic use Contact Lenses Cornea - microbiology Drug Therapy, Combination - administration & dosage Drug Therapy, Combination - therapeutic use Gases Humans Keratitis - etiology Keratitis - microbiology Keratoplasty, Penetrating Male Medical sciences Middle Aged Permeability Postoperative Complications Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the eye and orbit Ticarcillin - administration & dosage Ticarcillin - therapeutic use Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use |
| title | Alcaligenes xylosoxidans keratitis post penetrating keratoplasty in a rigid gas permeable lens wearer |
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