L-Glutamic acid gamma-monohydroxamate. A potentiator of vanadium-evoked glucose metabolism in vitro and in vivo

We report that the vanadium ligand L-Glu(gamma)HXM potentiates the capacity of free vanadium ions to activate glucose uptake and glucose metabolism in rat adipocytes in vitro (by 4-5-fold) and to lower blood glucose levels in hyperglycemic rats in vivo (by 5-7-fold). A molar ratio of two L-Glu(gamma...

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Veröffentlicht in:The Journal of biological chemistry 1999-09, Vol.274 (37), p.26617-26624
Hauptverfasser: Goldwaser, I, Li, J, Gershonov, E, Armoni, M, Karnieli, E, Fridkin, M, Shechter, Y
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Sprache:eng
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