Postoperative Spondylodiskitis: Etiology, Clinical Findings, Prognosis, and Comparison with Nonoperative Pyogenic Spondylodiskitis
We studied 31 cases of postoperative pyogenic spondylodiskitis (POS), comparing them with 72 cases of nonpostoperative pyogenic spondylodiskitis (NPOS). POS represents 30.1% of cases of pyogenic spondylodiskitis. The onset of symptoms occurred an average (±SD) of 27.7 (± 25.3) days following surgery...
Gespeichert in:
| Veröffentlicht in: | Clinical infectious diseases 1999-08, Vol.29 (2), p.339-345 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 345 |
|---|---|
| container_issue | 2 |
| container_start_page | 339 |
| container_title | Clinical infectious diseases |
| container_volume | 29 |
| creator | Jiménez-Mejías, Manuel E. de Dios Colmenero, Juan Sánchez-Lora, Fernando J. Palomino-Nicás, Julián Reguera, José M. García de la Heras, Joaquín García-Ordoñez, María A. Pachón, Jerónimo |
| description | We studied 31 cases of postoperative pyogenic spondylodiskitis (POS), comparing them with 72 cases of nonpostoperative pyogenic spondylodiskitis (NPOS). POS represents 30.1% of cases of pyogenic spondylodiskitis. The onset of symptoms occurred an average (±SD) of 27.7 (± 25.3) days following surgery. Predisposing factors were less frequent in POS than NPOS cases (P = .002). Neurological complications and inflammatory signs in the spine were more frequent with POS than with NPOS (P = .002 and P < .00001). Coagulase-negative Staphylococcus and anaerobic bacteria were more frequent in POS than in NPOS (P = .0001 and P = .05). Percutaneous bone biopsies yielded the etiology in 66.7% of cases, open bone biopsies in 100%, blood cultures in 55.6%, and cultures of adjacent foci in 94.4%. Eleven patients (35.5%) were cured with antimicrobial treatment, but surgical treatment was necessary in 64.5%. No relapses or deaths were recorded. Seventeen patients (54.8%) had severe functional sequelae, which were associated with inflammatory signs in the spine (P = .033), higher levels of leukocytosis (P = .05), higher erythrocyte sedimentation rates (P = .05), and paravertebral abscesses (P = .04). |
| doi_str_mv | 10.1086/520212 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_70011623</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>4460886</jstor_id><sourcerecordid>4460886</sourcerecordid><originalsourceid>FETCH-LOGICAL-c388t-f6ba00b78c5774d136c91926ce64a0ae38f3cf93f1ae5004eec169d60df0c7da3</originalsourceid><addsrcrecordid>eNplkU1v1DAQhi0Eoh_AL0AoB8SpgXGc2E5vaNVSaAWL-BDiYnltZ3GbtYMnW9grvxyvsuoicZqR3kfvSM8Q8oTCSwqSv2oqqGh1jxzShomSNy29n3doZFlLJg_IEeI1AKUSmofkgEItuGDtIfkzjzjGwSU9-ltXfBpisJs-Wo83fvR4WpyNPvZxuTkpZr0P3ui-OPfB-rDEk2Ke4jJE9HnVwRazuBp08hhD8cuPP4r3Meyr55u4dLngvxuPyINO9-ge7-Yx-XJ-9nl2UV59ePN29vqqNEzKsez4QgMshDSNELWljJuWthU3jtcatGOyY6ZrWUe1awBq5wzlreVgOzDCanZMXky9Q4o_1w5HtfJoXN_r4OIaldj64RXbgyZFxOQ6NSS_0mmjKKitbTXZzuCzXeN6sXL2H2zSm4HnO0BjNtclHYzHPddue0TGnk7Ydf5FuovrmoOUPMflFHsc3e-7WKcbla-IRl18-67gnfx6OYeP6pL9Be4Rob8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70011623</pqid></control><display><type>article</type><title>Postoperative Spondylodiskitis: Etiology, Clinical Findings, Prognosis, and Comparison with Nonoperative Pyogenic Spondylodiskitis</title><source>Jstor Complete Legacy</source><source>MEDLINE</source><source>Oxford University Press Journals Current</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Jiménez-Mejías, Manuel E. ; de Dios Colmenero, Juan ; Sánchez-Lora, Fernando J. ; Palomino-Nicás, Julián ; Reguera, José M. ; García de la Heras, Joaquín ; García-Ordoñez, María A. ; Pachón, Jerónimo</creator><creatorcontrib>Jiménez-Mejías, Manuel E. ; de Dios Colmenero, Juan ; Sánchez-Lora, Fernando J. ; Palomino-Nicás, Julián ; Reguera, José M. ; García de la Heras, Joaquín ; García-Ordoñez, María A. ; Pachón, Jerónimo</creatorcontrib><description>We studied 31 cases of postoperative pyogenic spondylodiskitis (POS), comparing them with 72 cases of nonpostoperative pyogenic spondylodiskitis (NPOS). POS represents 30.1% of cases of pyogenic spondylodiskitis. The onset of symptoms occurred an average (±SD) of 27.7 (± 25.3) days following surgery. Predisposing factors were less frequent in POS than NPOS cases (P = .002). Neurological complications and inflammatory signs in the spine were more frequent with POS than with NPOS (P = .002 and P < .00001). Coagulase-negative Staphylococcus and anaerobic bacteria were more frequent in POS than in NPOS (P = .0001 and P = .05). Percutaneous bone biopsies yielded the etiology in 66.7% of cases, open bone biopsies in 100%, blood cultures in 55.6%, and cultures of adjacent foci in 94.4%. Eleven patients (35.5%) were cured with antimicrobial treatment, but surgical treatment was necessary in 64.5%. No relapses or deaths were recorded. Seventeen patients (54.8%) had severe functional sequelae, which were associated with inflammatory signs in the spine (P = .033), higher levels of leukocytosis (P = .05), higher erythrocyte sedimentation rates (P = .05), and paravertebral abscesses (P = .04).</description><identifier>ISSN: 1058-4838</identifier><identifier>EISSN: 1537-6591</identifier><identifier>DOI: 10.1086/520212</identifier><identifier>PMID: 10476739</identifier><identifier>CODEN: CIDIEL</identifier><language>eng</language><publisher>Chicago, IL: The University of Chicago Press</publisher><subject>Abscesses ; Adolescent ; Adult ; Aged ; Biological and medical sciences ; Biopsies ; Blood ; Bones ; Clinical Articles ; Discitis ; Discitis - drug therapy ; Discitis - microbiology ; Discitis - physiopathology ; Erythrocyte sedimentation rate ; Etiology ; Female ; Humans ; Infections ; Male ; Medical sciences ; Middle Aged ; Orthopedic surgery ; Prognosis ; Spine - surgery ; Staphylococcus ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgical Wound Infection - drug therapy ; Surgical Wound Infection - microbiology ; Surgical Wound Infection - physiopathology ; Symptoms</subject><ispartof>Clinical infectious diseases, 1999-08, Vol.29 (2), p.339-345</ispartof><rights>Copyright 1999 The Infectious Diseases Society of America</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-f6ba00b78c5774d136c91926ce64a0ae38f3cf93f1ae5004eec169d60df0c7da3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/4460886$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/4460886$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,799,23909,23910,25118,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1920217$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10476739$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jiménez-Mejías, Manuel E.</creatorcontrib><creatorcontrib>de Dios Colmenero, Juan</creatorcontrib><creatorcontrib>Sánchez-Lora, Fernando J.</creatorcontrib><creatorcontrib>Palomino-Nicás, Julián</creatorcontrib><creatorcontrib>Reguera, José M.</creatorcontrib><creatorcontrib>García de la Heras, Joaquín</creatorcontrib><creatorcontrib>García-Ordoñez, María A.</creatorcontrib><creatorcontrib>Pachón, Jerónimo</creatorcontrib><title>Postoperative Spondylodiskitis: Etiology, Clinical Findings, Prognosis, and Comparison with Nonoperative Pyogenic Spondylodiskitis</title><title>Clinical infectious diseases</title><addtitle>Clinical Infectious Diseases</addtitle><description>We studied 31 cases of postoperative pyogenic spondylodiskitis (POS), comparing them with 72 cases of nonpostoperative pyogenic spondylodiskitis (NPOS). POS represents 30.1% of cases of pyogenic spondylodiskitis. The onset of symptoms occurred an average (±SD) of 27.7 (± 25.3) days following surgery. Predisposing factors were less frequent in POS than NPOS cases (P = .002). Neurological complications and inflammatory signs in the spine were more frequent with POS than with NPOS (P = .002 and P < .00001). Coagulase-negative Staphylococcus and anaerobic bacteria were more frequent in POS than in NPOS (P = .0001 and P = .05). Percutaneous bone biopsies yielded the etiology in 66.7% of cases, open bone biopsies in 100%, blood cultures in 55.6%, and cultures of adjacent foci in 94.4%. Eleven patients (35.5%) were cured with antimicrobial treatment, but surgical treatment was necessary in 64.5%. No relapses or deaths were recorded. Seventeen patients (54.8%) had severe functional sequelae, which were associated with inflammatory signs in the spine (P = .033), higher levels of leukocytosis (P = .05), higher erythrocyte sedimentation rates (P = .05), and paravertebral abscesses (P = .04).</description><subject>Abscesses</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Biopsies</subject><subject>Blood</subject><subject>Bones</subject><subject>Clinical Articles</subject><subject>Discitis</subject><subject>Discitis - drug therapy</subject><subject>Discitis - microbiology</subject><subject>Discitis - physiopathology</subject><subject>Erythrocyte sedimentation rate</subject><subject>Etiology</subject><subject>Female</subject><subject>Humans</subject><subject>Infections</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Orthopedic surgery</subject><subject>Prognosis</subject><subject>Spine - surgery</subject><subject>Staphylococcus</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgical Wound Infection - drug therapy</subject><subject>Surgical Wound Infection - microbiology</subject><subject>Surgical Wound Infection - physiopathology</subject><subject>Symptoms</subject><issn>1058-4838</issn><issn>1537-6591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkU1v1DAQhi0Eoh_AL0AoB8SpgXGc2E5vaNVSaAWL-BDiYnltZ3GbtYMnW9grvxyvsuoicZqR3kfvSM8Q8oTCSwqSv2oqqGh1jxzShomSNy29n3doZFlLJg_IEeI1AKUSmofkgEItuGDtIfkzjzjGwSU9-ltXfBpisJs-Wo83fvR4WpyNPvZxuTkpZr0P3ui-OPfB-rDEk2Ke4jJE9HnVwRazuBp08hhD8cuPP4r3Meyr55u4dLngvxuPyINO9-ge7-Yx-XJ-9nl2UV59ePN29vqqNEzKsez4QgMshDSNELWljJuWthU3jtcatGOyY6ZrWUe1awBq5wzlreVgOzDCanZMXky9Q4o_1w5HtfJoXN_r4OIaldj64RXbgyZFxOQ6NSS_0mmjKKitbTXZzuCzXeN6sXL2H2zSm4HnO0BjNtclHYzHPddue0TGnk7Ydf5FuovrmoOUPMflFHsc3e-7WKcbla-IRl18-67gnfx6OYeP6pL9Be4Rob8</recordid><startdate>19990801</startdate><enddate>19990801</enddate><creator>Jiménez-Mejías, Manuel E.</creator><creator>de Dios Colmenero, Juan</creator><creator>Sánchez-Lora, Fernando J.</creator><creator>Palomino-Nicás, Julián</creator><creator>Reguera, José M.</creator><creator>García de la Heras, Joaquín</creator><creator>García-Ordoñez, María A.</creator><creator>Pachón, Jerónimo</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19990801</creationdate><title>Postoperative Spondylodiskitis: Etiology, Clinical Findings, Prognosis, and Comparison with Nonoperative Pyogenic Spondylodiskitis</title><author>Jiménez-Mejías, Manuel E. ; de Dios Colmenero, Juan ; Sánchez-Lora, Fernando J. ; Palomino-Nicás, Julián ; Reguera, José M. ; García de la Heras, Joaquín ; García-Ordoñez, María A. ; Pachón, Jerónimo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-f6ba00b78c5774d136c91926ce64a0ae38f3cf93f1ae5004eec169d60df0c7da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Abscesses</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Biopsies</topic><topic>Blood</topic><topic>Bones</topic><topic>Clinical Articles</topic><topic>Discitis</topic><topic>Discitis - drug therapy</topic><topic>Discitis - microbiology</topic><topic>Discitis - physiopathology</topic><topic>Erythrocyte sedimentation rate</topic><topic>Etiology</topic><topic>Female</topic><topic>Humans</topic><topic>Infections</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Orthopedic surgery</topic><topic>Prognosis</topic><topic>Spine - surgery</topic><topic>Staphylococcus</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgical Wound Infection - drug therapy</topic><topic>Surgical Wound Infection - microbiology</topic><topic>Surgical Wound Infection - physiopathology</topic><topic>Symptoms</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jiménez-Mejías, Manuel E.</creatorcontrib><creatorcontrib>de Dios Colmenero, Juan</creatorcontrib><creatorcontrib>Sánchez-Lora, Fernando J.</creatorcontrib><creatorcontrib>Palomino-Nicás, Julián</creatorcontrib><creatorcontrib>Reguera, José M.</creatorcontrib><creatorcontrib>García de la Heras, Joaquín</creatorcontrib><creatorcontrib>García-Ordoñez, María A.</creatorcontrib><creatorcontrib>Pachón, Jerónimo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jiménez-Mejías, Manuel E.</au><au>de Dios Colmenero, Juan</au><au>Sánchez-Lora, Fernando J.</au><au>Palomino-Nicás, Julián</au><au>Reguera, José M.</au><au>García de la Heras, Joaquín</au><au>García-Ordoñez, María A.</au><au>Pachón, Jerónimo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Postoperative Spondylodiskitis: Etiology, Clinical Findings, Prognosis, and Comparison with Nonoperative Pyogenic Spondylodiskitis</atitle><jtitle>Clinical infectious diseases</jtitle><addtitle>Clinical Infectious Diseases</addtitle><date>1999-08-01</date><risdate>1999</risdate><volume>29</volume><issue>2</issue><spage>339</spage><epage>345</epage><pages>339-345</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><coden>CIDIEL</coden><abstract>We studied 31 cases of postoperative pyogenic spondylodiskitis (POS), comparing them with 72 cases of nonpostoperative pyogenic spondylodiskitis (NPOS). POS represents 30.1% of cases of pyogenic spondylodiskitis. The onset of symptoms occurred an average (±SD) of 27.7 (± 25.3) days following surgery. Predisposing factors were less frequent in POS than NPOS cases (P = .002). Neurological complications and inflammatory signs in the spine were more frequent with POS than with NPOS (P = .002 and P < .00001). Coagulase-negative Staphylococcus and anaerobic bacteria were more frequent in POS than in NPOS (P = .0001 and P = .05). Percutaneous bone biopsies yielded the etiology in 66.7% of cases, open bone biopsies in 100%, blood cultures in 55.6%, and cultures of adjacent foci in 94.4%. Eleven patients (35.5%) were cured with antimicrobial treatment, but surgical treatment was necessary in 64.5%. No relapses or deaths were recorded. Seventeen patients (54.8%) had severe functional sequelae, which were associated with inflammatory signs in the spine (P = .033), higher levels of leukocytosis (P = .05), higher erythrocyte sedimentation rates (P = .05), and paravertebral abscesses (P = .04).</abstract><cop>Chicago, IL</cop><pub>The University of Chicago Press</pub><pmid>10476739</pmid><doi>10.1086/520212</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1058-4838 |
| ispartof | Clinical infectious diseases, 1999-08, Vol.29 (2), p.339-345 |
| issn | 1058-4838 1537-6591 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70011623 |
| source | Jstor Complete Legacy; MEDLINE; Oxford University Press Journals Current; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Abscesses Adolescent Adult Aged Biological and medical sciences Biopsies Blood Bones Clinical Articles Discitis Discitis - drug therapy Discitis - microbiology Discitis - physiopathology Erythrocyte sedimentation rate Etiology Female Humans Infections Male Medical sciences Middle Aged Orthopedic surgery Prognosis Spine - surgery Staphylococcus Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgical Wound Infection - drug therapy Surgical Wound Infection - microbiology Surgical Wound Infection - physiopathology Symptoms |
| title | Postoperative Spondylodiskitis: Etiology, Clinical Findings, Prognosis, and Comparison with Nonoperative Pyogenic Spondylodiskitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T09%3A13%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Postoperative%20Spondylodiskitis:%20Etiology,%20Clinical%20Findings,%20Prognosis,%20and%20Comparison%20with%20Nonoperative%20Pyogenic%20Spondylodiskitis&rft.jtitle=Clinical%20infectious%20diseases&rft.au=Jim%C3%A9nez-Mej%C3%ADas,%20Manuel%20E.&rft.date=1999-08-01&rft.volume=29&rft.issue=2&rft.spage=339&rft.epage=345&rft.pages=339-345&rft.issn=1058-4838&rft.eissn=1537-6591&rft.coden=CIDIEL&rft_id=info:doi/10.1086/520212&rft_dat=%3Cjstor_proqu%3E4460886%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70011623&rft_id=info:pmid/10476739&rft_jstor_id=4460886&rfr_iscdi=true |