Targeted gene correction: a new strategy for molecular medicine

Advances, over the past 20 years, in the genetic manipulation of mammalian cells form the scientific basis of gene therapy. A number of strategies are presently being used to replace or augment a dysfunctional gene with a correct copy of itself. Now, a novel approach to correct the dysfunctional gen...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular medicine today (Regul. ed.) 1998-10, Vol.4 (10), p.431-437
Hauptverfasser:	Ye, Shanzhang, Cole-Strauss, Allyson, Frank, Bruce, Kmiec, Eric B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals chimeric chromosome Gene Targeting gene therapy Gene Transfer Techniques genetic correction Genetic Therapy homologous recombination Humans inherited mutation Oligonucleotides Phenotype
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!