Measurement of serosal temperatures and depth of thermal injury generated by thermal balloon endometrial ablation in ex vivo and in vivo models

Objective: To evaluate the safety profile of endometrial ablation performed with a thermal balloon as defined by serosal temperature elevation and depth of injury. Design: Observational study with histopathologic correlation conducted in ex vivo and in vivo phases. Setting: Academic medical center. Patient(s): Twenty patients undergoing total abdominal hysterectomy. Intervention(s): Endometrial ablation with a thermal balloon. Main Outcome Measure(s): Serosal temperature elevation and histologic depth of injury. Result(s): Ex vivo phase results revealed serosal temperatures remained within a safe physiologic range (