Activated calphostin C cytotoxicity is independent of p53 status and in vivo metastatic potential

The development of novel therapeutic agents to modulate programmed cell death independent of genetic background or malignant potential is a primary goal of modern cancer therapy. In this report, the light activation- and concentration-dependent cytotoxicity of calphostin C, a photoactivatable peryle...

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Veröffentlicht in:	Clinical cancer research 1998-10, Vol.4 (10), p.2391-2398
Hauptverfasser:	DUBAUSKAS, Z, BECK, T. P, CHMURA, S. J, KOVAR, D. A, KADKHODAIAN, M. M, SHRIVASTAV, M, CHUNG, T, STADLER, W. M, RINKER-SCHAEFFER, C. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics, Antineoplastic - pharmacology Antineoplastic agents Apoptosis Biological and medical sciences Biotransformation General aspects Humans Light Male Medical sciences Naphthalenes - pharmacokinetics Naphthalenes - pharmacology Neoplasm Metastasis Pharmacology. Drug treatments Rats Tumor Cells, Cultured Tumor Suppressor Protein p53 - analysis
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