Cellular distribution of iron in the brain of the Belgrade rat

In this study, we investigated the cellular distribution of iron in the brain of Belgrade rats. These rats have a mutation in Divalent Metal Transporter 1, which has been implicated in iron transport from endosomes. The Belgrade rats have iron-positive pyramidal neurons, but these are fewer in numbe...

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Veröffentlicht in:	Neuroscience 1999-08, Vol.93 (3), p.1189-1196
Hauptverfasser:	Burdo, J.R., Martin, J., Menzies, S.L., Dolan, K.G., Romano, M.A., Fletcher, R.J., Garrick, M.D., Garrick, L.M., Connor, J.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Anatomy Anemia, Hypochromic - genetics Anemia, Hypochromic - metabolism Animals Astrocytes - chemistry Belgrade rat Biological and medical sciences Brain Chemistry Carrier Proteins - genetics Carrier Proteins - metabolism Cation Transport Proteins Central nervous system Crosses, Genetic Diet Divalent Metal Transporter 1 Endosomes - metabolism Female Fundamental and applied biological sciences. Psychology glia Iron - analysis iron staining Iron-Binding Proteins Male Membrane Proteins - deficiency Membrane Proteins - genetics Membrane Proteins - metabolism Nerve Tissue Proteins - deficiency Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism neurons Neurons - metabolism Oligodendroglia - chemistry Oligodendroglia - pathology Organ Specificity Point Mutation Rats Rats, Inbred F344 Rats, Mutant Strains - metabolism Rats, Wistar tanycytes Vertebrates: nervous system and sense organs
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