Estrogen Regulates the Association of Intermediate Filament Proteins with Nuclear DNA in Human Breast Cancer Cells

In a previous study we showed that the levels of the intermediate filament proteins, cytokeratins 8, 18, and 19, in the nuclear matrix-intermediate filament (NM-IF) fraction from the hormone-dependent and estrogen receptor (ER)-positive human breast cancer cell line T-47D5 were regulated by estrogen...

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Veröffentlicht in:	The Journal of biological chemistry 1998-10, Vol.273 (44), p.29093-29097
Hauptverfasser:	Spencer, Virginia A., Coutts, Amanda S., Samuel, Shanti K., Murphy, Leigh C., Davie, James R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Nucleus - metabolism Cisplatin - metabolism DNA Adducts - metabolism DNA, Neoplasm - metabolism Estradiol - analogs & derivatives Estradiol - pharmacology Estrogen Antagonists - pharmacology Estrogens - pharmacology Humans Intermediate Filament Proteins - metabolism Keratins - metabolism Polyunsaturated Alkamides Tumor Cells, Cultured
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