Effects of Cysteinyl-Leukotriene Receptor Antagonist, Thromboxane A2 Receptor Antagonist, and Thromboxane A2 Synthetase Inhibitor on Antigen-Induced Bronchoconstriction in Patients With Asthma

Leukotriene (LT) and thromboxane A2 (TXA2) receptor antagonists have been used in the treatment of asthma. : We examined the effects of an LT receptor antagonist, TXA2 receptor antagonist, and TXA2 synthetase inhibitor on bronchoprovocation test (BPT) in patients with mild-to-moderate atopic asthma....

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Veröffentlicht in:	Chest 1998-10, Vol.114 (4), p.1028-1032
Hauptverfasser:	Obase, Yasushi, Shimoda, Terufumi, Matsuo, Nobuko, Matsuse, Hiroto, Asai, Sadahiro, Kohno, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Anti-Asthmatic Agents - administration & dosage Anti-Asthmatic Agents - therapeutic use antigen-induced bronchoconstriction Antigens - adverse effects Asthma - blood Asthma - diagnosis Asthma - drug therapy Asthma - etiology Benzoquinones - therapeutic use Biological and medical sciences Blood Proteins - metabolism Bronchial Provocation Tests Bronchoconstriction - drug effects chemical mediators Chromones - therapeutic use Chronic obstructive pulmonary disease, asthma Cross-Over Studies cysteinyl-leukotriene receptor antagonist Eosinophil Granule Proteins Female Follow-Up Studies Heptanoic Acids - therapeutic use Histamine - blood Humans Leukotriene Antagonists Male Medical sciences Membrane Proteins Methacrylates - therapeutic use Pneumology Receptors, Leukotriene - blood Receptors, Thromboxane - antagonists & inhibitors Receptors, Thromboxane - blood Ribonucleases thromboxane A2 receptor antagonist thromboxane A2 synthetase inhibitor Thromboxane B2 - analogs & derivatives Thromboxane B2 - blood Thromboxane-A Synthase - antagonists & inhibitors Thromboxane-A Synthase - blood Treatment Outcome
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