Abnormal regulation of aortic NOS2 and NOS3 activity and expression from portal vein‐stenosed rats after lipopolysaccharide administration

Hyporeactivity to vasoconstrictors in aortae from portal vein‐stenosed rats is associated with an increased activity of endothelial NO synthase (NOS3). In contrast, during sepsis, which is common in cirrhosis, vascular hyporeactivity is associated with an induction of inducible NOS2. The aim of this...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1999-09, Vol.30 (3), p.698-704
Hauptverfasser:	Heller, Jörg, Sogni, Philippe, Tazi, Khalid A., Chagneau, Carine, Poirel, Odile, Moreau, Richard, Lebrec, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - enzymology Biological and medical sciences Digestive system Hypertension, Portal - enzymology Investigative techniques, diagnostic techniques (general aspects) Lipopolysaccharides - pharmacology Male Medical sciences Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II Nitric Oxide Synthase Type III Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Phenylephrine - pharmacology Portal Vein Rats Rats, Sprague-Dawley
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