A review of randomized clinical trials of antibiotic therapy in preterm premature rupture of the membranes

Rupture of membranes before 37 completed weeks of gestation, and before the onset of contractions occurs among 2-3% of pregnancies, and in about 30%-40% of women who deliver preterm. It is known as preterm premature rupture of membranes (PPROM) and is associated with maternal and neonatal morbidity....

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Veröffentlicht in:Archives of gynecology and obstetrics 1998-08, Vol.261 (4), p.173-181
Hauptverfasser: Maymon, E, Chaim, W, Sheiner, E, Mazor, M
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container_title Archives of gynecology and obstetrics
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creator Maymon, E
Chaim, W
Sheiner, E
Mazor, M
description Rupture of membranes before 37 completed weeks of gestation, and before the onset of contractions occurs among 2-3% of pregnancies, and in about 30%-40% of women who deliver preterm. It is known as preterm premature rupture of membranes (PPROM) and is associated with maternal and neonatal morbidity. It has been postulated that antibiotic therapy may significantly decrease the complications associated with infection. The aim of the present review is to summarize the available data about the value of antibiotic therapy in PPROM.
doi_str_mv 10.1007/s004040050218
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subjects Anti-Bacterial Agents - therapeutic use
Antibiotics
Chorioamnionitis - prevention & control
Female
Fetal Membranes, Premature Rupture - drug therapy
Humans
Infant, Newborn
Pregnancy
Randomized Controlled Trials as Topic
Treatment Outcome
title A review of randomized clinical trials of antibiotic therapy in preterm premature rupture of the membranes
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