Regulation of cell survival during B lymphopoiesis: suppressed apoptosis of pro‐B cells in P53‐deficient mouse bone marrow

B cell development in mouse bone marrow (BM) is subject to quality controls that eliminate aberrant cells by apoptosis, but the intrinsic cellular mechanisms that mediate this negative B cell selection remain unclear. The p53 tumor suppressor transduces signals resulting in apoptosis and cell cycle...

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