Effect of suplatast tosilate (IPD-1151T) on cytokine production by allergen-specific human Th1 and Th2 cell lines

Suplatast tosilate (IPD-1151T) is an antiallergic agent that suppresses airway eosinophil infiltration in asthma. We investigated the effects of IPD-1151T on proliferative response and cytokine production by human antigen-specific T cell lines. Purified protein derivatives (PPD)-specific T helper 1...

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Veröffentlicht in:	Life sciences (1973) 1999-07, Vol.65 (8), p.763-770
Hauptverfasser:	Oda, Naruhito, Minoguchi, Kenji, Yokoe, Takuya, Hashimoto, Tadanori, Wada, Kiyoko, Miyamoto, Masahide, Tanaka, Akihiko, Kohno, Yasurou, Adachi, Mitsuru
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Allergens - immunology Animals Anti-Allergic Agents - pharmacology antiallergic agent Antigens, Dermatophagoides Arylsulfonates - pharmacology Cell Division - drug effects Cell Line Cytokines - metabolism Epitopes - drug effects Glycoproteins - immunology Humans IFN-γ IL-4 IL-5 Interferon-gamma - metabolism Mites - immunology Sulfonium Compounds - pharmacology Th1 cells Th1 Cells - cytology Th1 Cells - immunology Th1 Cells - metabolism Th2 cells Th2 Cells - cytology Th2 Cells - immunology Th2 Cells - metabolism
Online-Zugang:	Volltext
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