Chemokine Receptors and their Crucial Role in Human Immunodeficiency Virus Infection: Major Breakthroughs in HIV Research
Within the last three years, major progress in the understanding of acquired immune deficiency syndrome pathogenesis has been achieved. The discovery that human immunodeficiency virus (HIV), in addition to the CD4 receptor, requires the presence of a coreceptor in order to infect cells has led to a...
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| Veröffentlicht in: | Scandinavian journal of immunology 1998-10, Vol.48 (4), p.339-346 |
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| container_end_page | 346 |
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| container_title | Scandinavian journal of immunology |
| container_volume | 48 |
| creator | Kristiansen Knudsen Eugen‐Olsen |
| description | Within the last three years, major progress in the understanding of acquired immune deficiency syndrome pathogenesis has been achieved. The discovery that human immunodeficiency virus (HIV), in addition to the CD4 receptor, requires the presence of a coreceptor in order to infect cells has led to a series of breakthroughs in HIV research and knowledge. These include an increased understanding of viral entry, a connection of viral phenotype to specific coreceptor use, and an unequivocal linkage of a single human gene to host susceptibility. All in all these achievements provide a number of promising new strategies for combating HIV. |
| doi_str_mv | 10.1046/j.1365-3083.1998.00438.x |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0300-9475 |
| ispartof | Scandinavian journal of immunology, 1998-10, Vol.48 (4), p.339-346 |
| issn | 0300-9475 1365-3083 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69988678 |
| source | Wiley Free Content; MEDLINE; IngentaConnect Free/Open Access Journals; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | AIDS/HIV HIV Infections - immunology HIV Infections - virology HIV-1 - physiology HIV-2 - physiology Human immunodeficiency virus Humans Receptors, Chemokine - physiology Receptors, Virus - physiology Virus Replication - immunology |
| title | Chemokine Receptors and their Crucial Role in Human Immunodeficiency Virus Infection: Major Breakthroughs in HIV Research |
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