Magnetic resonance imaging differentiates between necrotizing and non-necrotizing fasciitis of the lower extremity
Background: Distinction between uncomplicated infective fasciitis and early necrotizing fasciitis can be extremely difficult without operation, yet the management and prognosis of both conditions depend greatly on early recognition and assessment of the extent of involvement. Study Design: This was...
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Veröffentlicht in: | Journal of the American College of Surgeons 1998-10, Vol.187 (4), p.416-421 |
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creator | Brothers, Thomas E Tagge, Derya U Stutley, Jennifer E Conway, William F Del Schutte, H Byrne, T.Karl |
description | Background: Distinction between uncomplicated infective fasciitis and early necrotizing fasciitis can be extremely difficult without operation, yet the management and prognosis of both conditions depend greatly on early recognition and assessment of the extent of involvement.
Study Design: This was a prospective review of the utility of magnetic resonance imaging (MRI) in nine patients with suspected infective or necrotizing fasciitis treated at an academic medical center or a Veterans Administration hospital.
Results: Magnetic resonance imaging documented fascial inflammation, characterized by low intensity on T
1-weighted images and high intensity on T
2-weighted images, in all nine patients. Absence of gadolinium contrast enhancement on T
1-weighted images reliably detected fascial necrosis in all six patients who required operative debridement. Magnetic resonance imaging was extremely useful in defining the extent of fasciitis and was more accurate in predicting necrosis or pyomyositis than was myoglobinuria or elevation of serum creatine kinase or lactate dehydrogenase. Operation was avoided in two patients without evidence of necrosis on MRI. One patient without evidence of necrosis, explored because of contradictory clinical findings, was confirmed at operation to have cellulitis without necrosis.
Conclusions: Magnetic resonance imaging with gadolinium contrast accurately determines the presence of necrosis and the need for operation in patients with fasciitis of the lower extremity. Preoperative determination of the extent of involvement facilitates operative planning. |
doi_str_mv | 10.1016/S1072-7515(98)00192-6 |
format | Article |
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Study Design: This was a prospective review of the utility of magnetic resonance imaging (MRI) in nine patients with suspected infective or necrotizing fasciitis treated at an academic medical center or a Veterans Administration hospital.
Results: Magnetic resonance imaging documented fascial inflammation, characterized by low intensity on T
1-weighted images and high intensity on T
2-weighted images, in all nine patients. Absence of gadolinium contrast enhancement on T
1-weighted images reliably detected fascial necrosis in all six patients who required operative debridement. Magnetic resonance imaging was extremely useful in defining the extent of fasciitis and was more accurate in predicting necrosis or pyomyositis than was myoglobinuria or elevation of serum creatine kinase or lactate dehydrogenase. Operation was avoided in two patients without evidence of necrosis on MRI. One patient without evidence of necrosis, explored because of contradictory clinical findings, was confirmed at operation to have cellulitis without necrosis.
Conclusions: Magnetic resonance imaging with gadolinium contrast accurately determines the presence of necrosis and the need for operation in patients with fasciitis of the lower extremity. Preoperative determination of the extent of involvement facilitates operative planning.</description><identifier>ISSN: 1072-7515</identifier><identifier>EISSN: 1879-1190</identifier><identifier>DOI: 10.1016/S1072-7515(98)00192-6</identifier><identifier>PMID: 9783789</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Anti-Infective Agents - therapeutic use ; Biological and medical sciences ; Diagnosis, Differential ; Fasciitis - diagnosis ; Fasciitis - drug therapy ; Fasciitis - microbiology ; Fasciitis, Necrotizing - diagnosis ; Fasciitis, Necrotizing - drug therapy ; Fasciitis, Necrotizing - microbiology ; Female ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Leg - microbiology ; Leg - pathology ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Miscellaneous. Technology ; Patient Selection ; Predictive Value of Tests ; Prospective Studies ; Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><ispartof>Journal of the American College of Surgeons, 1998-10, Vol.187 (4), p.416-421</ispartof><rights>1998 The American College of Surgeons</rights><rights>1999 INIST-CNRS</rights><rights>Copyright Franklin H. Martin Memorial Foundation Oct 1998</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c511t-7235525bad1269bd4bab7d12721095d572a31b242dbb742b630766fd64a2dcc43</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1072751598001926$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,3537,23909,23910,25118,27901,27902,65306,69986</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1581313$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9783789$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brothers, Thomas E</creatorcontrib><creatorcontrib>Tagge, Derya U</creatorcontrib><creatorcontrib>Stutley, Jennifer E</creatorcontrib><creatorcontrib>Conway, William F</creatorcontrib><creatorcontrib>Del Schutte, H</creatorcontrib><creatorcontrib>Byrne, T.Karl</creatorcontrib><title>Magnetic resonance imaging differentiates between necrotizing and non-necrotizing fasciitis of the lower extremity</title><title>Journal of the American College of Surgeons</title><addtitle>J Am Coll Surg</addtitle><description>Background: Distinction between uncomplicated infective fasciitis and early necrotizing fasciitis can be extremely difficult without operation, yet the management and prognosis of both conditions depend greatly on early recognition and assessment of the extent of involvement.
Study Design: This was a prospective review of the utility of magnetic resonance imaging (MRI) in nine patients with suspected infective or necrotizing fasciitis treated at an academic medical center or a Veterans Administration hospital.
Results: Magnetic resonance imaging documented fascial inflammation, characterized by low intensity on T
1-weighted images and high intensity on T
2-weighted images, in all nine patients. Absence of gadolinium contrast enhancement on T
1-weighted images reliably detected fascial necrosis in all six patients who required operative debridement. Magnetic resonance imaging was extremely useful in defining the extent of fasciitis and was more accurate in predicting necrosis or pyomyositis than was myoglobinuria or elevation of serum creatine kinase or lactate dehydrogenase. Operation was avoided in two patients without evidence of necrosis on MRI. One patient without evidence of necrosis, explored because of contradictory clinical findings, was confirmed at operation to have cellulitis without necrosis.
Conclusions: Magnetic resonance imaging with gadolinium contrast accurately determines the presence of necrosis and the need for operation in patients with fasciitis of the lower extremity. Preoperative determination of the extent of involvement facilitates operative planning.</description><subject>Anti-Infective Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Diagnosis, Differential</subject><subject>Fasciitis - diagnosis</subject><subject>Fasciitis - drug therapy</subject><subject>Fasciitis - microbiology</subject><subject>Fasciitis, Necrotizing - diagnosis</subject><subject>Fasciitis, Necrotizing - drug therapy</subject><subject>Fasciitis, Necrotizing - microbiology</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Leg - microbiology</subject><subject>Leg - pathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous. Technology</subject><subject>Patient Selection</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Radiodiagnosis. Nmr imagery. 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Technology</topic><topic>Patient Selection</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brothers, Thomas E</creatorcontrib><creatorcontrib>Tagge, Derya U</creatorcontrib><creatorcontrib>Stutley, Jennifer E</creatorcontrib><creatorcontrib>Conway, William F</creatorcontrib><creatorcontrib>Del Schutte, H</creatorcontrib><creatorcontrib>Byrne, T.Karl</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Surgeons</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brothers, Thomas E</au><au>Tagge, Derya U</au><au>Stutley, Jennifer E</au><au>Conway, William F</au><au>Del Schutte, H</au><au>Byrne, T.Karl</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic resonance imaging differentiates between necrotizing and non-necrotizing fasciitis of the lower extremity</atitle><jtitle>Journal of the American College of Surgeons</jtitle><addtitle>J Am Coll Surg</addtitle><date>1998-10-01</date><risdate>1998</risdate><volume>187</volume><issue>4</issue><spage>416</spage><epage>421</epage><pages>416-421</pages><issn>1072-7515</issn><eissn>1879-1190</eissn><abstract>Background: Distinction between uncomplicated infective fasciitis and early necrotizing fasciitis can be extremely difficult without operation, yet the management and prognosis of both conditions depend greatly on early recognition and assessment of the extent of involvement.
Study Design: This was a prospective review of the utility of magnetic resonance imaging (MRI) in nine patients with suspected infective or necrotizing fasciitis treated at an academic medical center or a Veterans Administration hospital.
Results: Magnetic resonance imaging documented fascial inflammation, characterized by low intensity on T
1-weighted images and high intensity on T
2-weighted images, in all nine patients. Absence of gadolinium contrast enhancement on T
1-weighted images reliably detected fascial necrosis in all six patients who required operative debridement. Magnetic resonance imaging was extremely useful in defining the extent of fasciitis and was more accurate in predicting necrosis or pyomyositis than was myoglobinuria or elevation of serum creatine kinase or lactate dehydrogenase. Operation was avoided in two patients without evidence of necrosis on MRI. One patient without evidence of necrosis, explored because of contradictory clinical findings, was confirmed at operation to have cellulitis without necrosis.
Conclusions: Magnetic resonance imaging with gadolinium contrast accurately determines the presence of necrosis and the need for operation in patients with fasciitis of the lower extremity. Preoperative determination of the extent of involvement facilitates operative planning.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>9783789</pmid><doi>10.1016/S1072-7515(98)00192-6</doi><tpages>6</tpages></addata></record> |
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subjects | Anti-Infective Agents - therapeutic use Biological and medical sciences Diagnosis, Differential Fasciitis - diagnosis Fasciitis - drug therapy Fasciitis - microbiology Fasciitis, Necrotizing - diagnosis Fasciitis, Necrotizing - drug therapy Fasciitis, Necrotizing - microbiology Female Humans Investigative techniques, diagnostic techniques (general aspects) Leg - microbiology Leg - pathology Magnetic Resonance Imaging Male Medical sciences Miscellaneous. Technology Patient Selection Predictive Value of Tests Prospective Studies Radiodiagnosis. Nmr imagery. Nmr spectrometry |
title | Magnetic resonance imaging differentiates between necrotizing and non-necrotizing fasciitis of the lower extremity |
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