Loss of Heterozygosity at D14S62 and Metastatic Potential of Breast Cancer

BACKGROUND: In breast cancer progression, the prevalence of damage at specific genetic loci often increases with the stage of the lesion (i.e., from noninvasive to invasive to metastatic). By use of genetic markers and analysis of allelic imbalances (loss of heterozygosity [ LOH]) to compare DNA sam...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1999-08, Vol.91 (16), p.1391-1397
Hauptverfasser:	O'Connell, Peter, Fischbach, Kathryn, Hilsenbeck, Susan, Mohsin, Syed K., Fuqua, Suzanne A. W., Clark, Gary M., Osborne, C. Kent, Allred, D. Craig
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers, Tumor - genetics Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Chromosomes, Human, Pair 14 - genetics DNA Primers DNA, Neoplasm - genetics Female Genetics Gynecology. Andrology. Obstetrics Humans Loss of Heterozygosity Lymphatic Metastasis Mammary gland diseases Medical research Medical sciences Mitotic Index Tumors
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