Serum surfactant protein A levels in healthy individuals are increased in smokers

Serum surfactant protein A levels in healthy individuals are increased in smokers

Serum levels of surfactant protein A (SP-A) were studied in 237 healthy subjects in relation to sex, age, and smoking habits. SP-A values in male smokers were significantly higher than those in male nonsmokers (p < 0.001). The amount of cigarette smoking did not correlate significantly with SP-A...

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Veröffentlicht in:Lung 1998-11, Vol.176 (6), p.355-361
Hauptverfasser: Nomori, H, Horio, H, Fuyuno, G, Kobayashi, R, Morinaga, S, Suemasu, K
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Age Factors
Aged
Child
Child, Preschool
Female
Glycoproteins
Humans
Infant
Infant, Newborn
Male
Middle Aged
Proteolipids - blood
Pulmonary Surfactant-Associated Protein A
Pulmonary Surfactant-Associated Proteins
Pulmonary Surfactants - blood
Reference Values
Sex Factors
Smoking - blood
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Zusammenfassung:Serum levels of surfactant protein A (SP-A) were studied in 237 healthy subjects in relation to sex, age, and smoking habits. SP-A values in male smokers were significantly higher than those in male nonsmokers (p < 0.001). The amount of cigarette smoking did not correlate significantly with SP-A values, however. SP-A values in young nonsmoking males and females were somewhat lower than those in older, but without significant difference. No significant difference in values was found between the sexes. We conclude that (1) smoking increases serum levels of SP-A, and (2) SP-A serum levels are not affected by age and sex.
ISSN:0341-2040
1432-1750
DOI:10.1007/pl00007617