Bone mineral metabolism in pediatric inflammatory bowel disease
The development of reliable techniques to measure bone densitometry and evolving effective drug treatment have kindled great interest in the diagnosis and treatment of osteoporosis in adults with inflammatory bowel disease. A number of studies have examined the prevalence of abnormal bone mineral me...
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| Veröffentlicht in: | Inflammatory bowel diseases 1999-08, Vol.5 (3), p.192-199 |
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| container_title | Inflammatory bowel diseases |
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| creator | Issenman, R M |
| description | The development of reliable techniques to measure bone densitometry and evolving effective drug treatment have kindled great interest in the diagnosis and treatment of osteoporosis in adults with inflammatory bowel disease. A number of studies have examined the prevalence of abnormal bone mineral metabolism in children and adolescents. Studies, conducted over the past decade, indicate a greater likelihood of clinically significant problems in Crohn's disease than in ulcerative colitis. Corticosteroids have been proven to impair bone mineral status. It is increasingly clear that inflammation and other factors play a bigger role than malabsorbtion of minerals or vitamin D in most patients. As the use of the bisphonate class of drugs is limited in pediatric patients, there is a need to emphasize the role of diet and exercise in children and teenagers, particularly in those affected by inflammatory bowel disease. |
| doi_str_mv | 10.1097/00054725-199908000-00008 |
| format | Article |
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| ispartof | Inflammatory bowel diseases, 1999-08, Vol.5 (3), p.192-199 |
| issn | 1078-0998 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69973046 |
| source | MEDLINE; Wiley Journals; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Absorptiometry, Photon Adolescent Adult Bone Density Bone Development - drug effects Bone Diseases, Metabolic - etiology Bone Diseases, Metabolic - physiopathology Bone Diseases, Metabolic - prevention & control Child Diphosphonates - therapeutic use Female Humans Inflammatory Bowel Diseases - complications Inflammatory Bowel Diseases - drug therapy Inflammatory Bowel Diseases - physiopathology Malabsorption Syndromes - etiology Male Nutrition Disorders - etiology |
| title | Bone mineral metabolism in pediatric inflammatory bowel disease |
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