Association of Focal Adhesion Kinase with Grb7 and Its Role in Cell Migration

Focal adhesion kinase (FAK) has been implicated to play a key role in integrin-mediated signal transduction in cell migration. Grb7 is an Src homology (SH) 2-containing and pleckstrin homology domain-containing molecule, which shares significant homology with the Caenorhabditis elegans gene for Mig-...

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Veröffentlicht in:	The Journal of biological chemistry 1999-08, Vol.274 (34), p.24425-24430
Hauptverfasser:	Han, Dong Cho, Guan, Jun-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Amino Acid Sequence Animals Cell Adhesion Cell Adhesion Molecules - physiology Cell Movement Focal Adhesion Kinase 1 Focal Adhesion Protein-Tyrosine Kinases GRB7 Adaptor Protein Humans Mice Molecular Sequence Data Phosphorylation Protein-Tyrosine Kinases - physiology Proteins - physiology src Homology Domains Transfection
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