Characterization of cd44v6 isoforms in head‐and‐neck squamous‐cell carcinoma

CD44 splice variants, especially those containing the v6 domain, are assumed to play a critical role in the malignant progression of many human tumors. This concept was based on (i) the aberrant expression of CD44v6 in malignant cells, often encoded by alternatively spliced transcripts, and (ii) the...

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Veröffentlicht in:	International journal of cancer 1999-09, Vol.82 (6), p.837-845
Hauptverfasser:	Van Hal, Nicole L.W., van Dongen, Guus A.M.S., Stigter‐Van Walsum, Marijke, Snow, Gordon B., Brakenhoff, Ruud H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Biological and medical sciences Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - pathology Genetic Variation Glycoproteins - analysis Glycoproteins - genetics Head and Neck Neoplasms - genetics Head and Neck Neoplasms - immunology Head and Neck Neoplasms - pathology Humans Hyaluronan Receptors - analysis Hyaluronan Receptors - genetics Immunohistochemistry Medical sciences Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Protein Isoforms - analysis Protein Isoforms - genetics Reverse Transcriptase Polymerase Chain Reaction Tumor Cells, Cultured Tumors
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