Comparative Study of Mortality and Morbidity in Premature Infants (Birth Weight, <1,250 g) with Candidemia or Candidal Meningitis
Little information is available on long-term neurodevelopment of premature neonates with invasive candidal infections. We retrospectively studied the outcomes for 25 premature neonates (birth weight, .05), and 29% (4 of 14) of surviving cases and 14% (3 of 21) of controls were disabled (P > .05)...
Gespeichert in:
| Veröffentlicht in: | Clinical infectious diseases 1998-09, Vol.27 (3), p.559-565 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 565 |
|---|---|
| container_issue | 3 |
| container_start_page | 559 |
| container_title | Clinical infectious diseases |
| container_volume | 27 |
| creator | Lee, Bonita E. Cheung, Po-Yin Robinson, Joan L. Evanochko, Christene Robertson, Charlene M. T. |
| description | Little information is available on long-term neurodevelopment of premature neonates with invasive candidal infections. We retrospectively studied the outcomes for 25 premature neonates (birth weight, .05), and 29% (4 of 14) of surviving cases and 14% (3 of 21) of controls were disabled (P > .05). More cases had combined mortality and neurodevelopmental disabilities than did controls (60% vs. 28%, respectively; P < .05). Use of invasive therapies should be minimized for premature neonates at risk for invasive candidal infection that is associated with adverse outcomes. |
| doi_str_mv | 10.1086/514712 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_69959901</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>4460587</jstor_id><sourcerecordid>4460587</sourcerecordid><originalsourceid>FETCH-LOGICAL-c425t-6dd0decc257ad70eb500a7ec97e8ff1f2e74ecaea897ae651c70a602fbe352393</originalsourceid><addsrcrecordid>eNqFkUtv1DAUhSMEKqXALwDJC1SB1IDtxLEtsSkj6FTqAOJV1I11x76Zus1jsB1glvxzMppoWLKyz_0-nc3JsseMvmRUVa8EKyXjd7JDJgqZV0Kzu-OfCpWXqlD3swcx3lDKmKLiIDvQUlIm5GH2Z9a3awiQ_E8kn9PgNqSvyaIPCRqfNgQ6t01L77bJd-RjwBbSEJCcdzV0KZLnb3xI1-QS_eo6nZDX7IQLSlYvyC8_nmdjg3fYeiB9mBI0ZIGd71Y--fgwu1dDE_HR9B5lX9-9_TKb5xcfzs5npxe5LblIeeUcdWgtFxKcpLgUlIJEqyWqumY1R1miBQSlJWAlmJUUKsrrJRaCF7o4yo53vevQ_xgwJtP6aLFpoMN-iKbSWmhN2X9FJoUUpZb_RBv6GAPWZh18C2FjGDXbUcxulFF8OjUOyxbdXptWGPmziUO00NQBOuvjXuOFrBRXo_Zkp93E1Ic9LstqnHnbku-wjwl_7zGEW1PJQgoz_35lzsTVt0-X8_dmUfwFlgyrww</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17575497</pqid></control><display><type>article</type><title>Comparative Study of Mortality and Morbidity in Premature Infants (Birth Weight, <1,250 g) with Candidemia or Candidal Meningitis</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Lee, Bonita E. ; Cheung, Po-Yin ; Robinson, Joan L. ; Evanochko, Christene ; Robertson, Charlene M. T.</creator><creatorcontrib>Lee, Bonita E. ; Cheung, Po-Yin ; Robinson, Joan L. ; Evanochko, Christene ; Robertson, Charlene M. T.</creatorcontrib><description>Little information is available on long-term neurodevelopment of premature neonates with invasive candidal infections. We retrospectively studied the outcomes for 25 premature neonates (birth weight, <1,250 g) with candidemia or candidal meningitis (cases) and compared them with 25 neonates matched for birth weight (±100 g) and gestational age (±1 week) (controls). Durations of antibiotic therapy, artificial ventilation, invasive catheterizations, and hyperalimentation were longer for cases than for controls. Cases had a higher final grade of intraventricular hemorrhage than did controls (median: 3.0 vs. 2.5, respectively; P < .05). Forty-four percent (11 of 25) of cases and 16% (4 of 25) of controls died (P > .05), and 29% (4 of 14) of surviving cases and 14% (3 of 21) of controls were disabled (P > .05). More cases had combined mortality and neurodevelopmental disabilities than did controls (60% vs. 28%, respectively; P < .05). Use of invasive therapies should be minimized for premature neonates at risk for invasive candidal infection that is associated with adverse outcomes.</description><identifier>ISSN: 1058-4838</identifier><identifier>EISSN: 1537-6591</identifier><identifier>DOI: 10.1086/514712</identifier><identifier>PMID: 9770157</identifier><identifier>CODEN: CIDIEL</identifier><language>eng</language><publisher>Chicago, IL: The University Chicago Press</publisher><subject>Biological and medical sciences ; Birth weight ; Blood ; Candida ; Candida - isolation & purification ; Candidemia ; Candidiasis - complications ; Candidiasis - drug therapy ; Candidiasis - epidemiology ; Candidiasis - mortality ; Case-Control Studies ; Catheters ; Clinical Articles ; Demography ; Dosage ; Human mycoses ; Humans ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases - drug therapy ; Infant, Premature, Diseases - epidemiology ; Infant, Premature, Diseases - mortality ; Infant, Very Low Birth Weight ; Infants ; Infections ; Infectious diseases ; Medical sciences ; Meningitis, Fungal - complications ; Meningitis, Fungal - drug therapy ; Meningitis, Fungal - epidemiology ; Meningitis, Fungal - mortality ; Morbidity ; Mortality ; Mycoses ; Mycoses of the nervous system ; Newborns ; Pediatrics ; Retrospective Studies ; Risk Factors ; Treatment Outcome</subject><ispartof>Clinical infectious diseases, 1998-09, Vol.27 (3), p.559-565</ispartof><rights>Copyright 1998 The Infectious Diseases Society of America</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c425t-6dd0decc257ad70eb500a7ec97e8ff1f2e74ecaea897ae651c70a602fbe352393</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/4460587$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/4460587$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2376828$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9770157$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Bonita E.</creatorcontrib><creatorcontrib>Cheung, Po-Yin</creatorcontrib><creatorcontrib>Robinson, Joan L.</creatorcontrib><creatorcontrib>Evanochko, Christene</creatorcontrib><creatorcontrib>Robertson, Charlene M. T.</creatorcontrib><title>Comparative Study of Mortality and Morbidity in Premature Infants (Birth Weight, <1,250 g) with Candidemia or Candidal Meningitis</title><title>Clinical infectious diseases</title><addtitle>Clinical Infectious Diseases</addtitle><description>Little information is available on long-term neurodevelopment of premature neonates with invasive candidal infections. We retrospectively studied the outcomes for 25 premature neonates (birth weight, <1,250 g) with candidemia or candidal meningitis (cases) and compared them with 25 neonates matched for birth weight (±100 g) and gestational age (±1 week) (controls). Durations of antibiotic therapy, artificial ventilation, invasive catheterizations, and hyperalimentation were longer for cases than for controls. Cases had a higher final grade of intraventricular hemorrhage than did controls (median: 3.0 vs. 2.5, respectively; P < .05). Forty-four percent (11 of 25) of cases and 16% (4 of 25) of controls died (P > .05), and 29% (4 of 14) of surviving cases and 14% (3 of 21) of controls were disabled (P > .05). More cases had combined mortality and neurodevelopmental disabilities than did controls (60% vs. 28%, respectively; P < .05). Use of invasive therapies should be minimized for premature neonates at risk for invasive candidal infection that is associated with adverse outcomes.</description><subject>Biological and medical sciences</subject><subject>Birth weight</subject><subject>Blood</subject><subject>Candida</subject><subject>Candida - isolation & purification</subject><subject>Candidemia</subject><subject>Candidiasis - complications</subject><subject>Candidiasis - drug therapy</subject><subject>Candidiasis - epidemiology</subject><subject>Candidiasis - mortality</subject><subject>Case-Control Studies</subject><subject>Catheters</subject><subject>Clinical Articles</subject><subject>Demography</subject><subject>Dosage</subject><subject>Human mycoses</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Infant, Premature, Diseases - drug therapy</subject><subject>Infant, Premature, Diseases - epidemiology</subject><subject>Infant, Premature, Diseases - mortality</subject><subject>Infant, Very Low Birth Weight</subject><subject>Infants</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Meningitis, Fungal - complications</subject><subject>Meningitis, Fungal - drug therapy</subject><subject>Meningitis, Fungal - epidemiology</subject><subject>Meningitis, Fungal - mortality</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Mycoses</subject><subject>Mycoses of the nervous system</subject><subject>Newborns</subject><subject>Pediatrics</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Treatment Outcome</subject><issn>1058-4838</issn><issn>1537-6591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtv1DAUhSMEKqXALwDJC1SB1IDtxLEtsSkj6FTqAOJV1I11x76Zus1jsB1glvxzMppoWLKyz_0-nc3JsseMvmRUVa8EKyXjd7JDJgqZV0Kzu-OfCpWXqlD3swcx3lDKmKLiIDvQUlIm5GH2Z9a3awiQ_E8kn9PgNqSvyaIPCRqfNgQ6t01L77bJd-RjwBbSEJCcdzV0KZLnb3xI1-QS_eo6nZDX7IQLSlYvyC8_nmdjg3fYeiB9mBI0ZIGd71Y--fgwu1dDE_HR9B5lX9-9_TKb5xcfzs5npxe5LblIeeUcdWgtFxKcpLgUlIJEqyWqumY1R1miBQSlJWAlmJUUKsrrJRaCF7o4yo53vevQ_xgwJtP6aLFpoMN-iKbSWmhN2X9FJoUUpZb_RBv6GAPWZh18C2FjGDXbUcxulFF8OjUOyxbdXptWGPmziUO00NQBOuvjXuOFrBRXo_Zkp93E1Ic9LstqnHnbku-wjwl_7zGEW1PJQgoz_35lzsTVt0-X8_dmUfwFlgyrww</recordid><startdate>19980901</startdate><enddate>19980901</enddate><creator>Lee, Bonita E.</creator><creator>Cheung, Po-Yin</creator><creator>Robinson, Joan L.</creator><creator>Evanochko, Christene</creator><creator>Robertson, Charlene M. T.</creator><general>The University Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>19980901</creationdate><title>Comparative Study of Mortality and Morbidity in Premature Infants (Birth Weight, <1,250 g) with Candidemia or Candidal Meningitis</title><author>Lee, Bonita E. ; Cheung, Po-Yin ; Robinson, Joan L. ; Evanochko, Christene ; Robertson, Charlene M. T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c425t-6dd0decc257ad70eb500a7ec97e8ff1f2e74ecaea897ae651c70a602fbe352393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Biological and medical sciences</topic><topic>Birth weight</topic><topic>Blood</topic><topic>Candida</topic><topic>Candida - isolation & purification</topic><topic>Candidemia</topic><topic>Candidiasis - complications</topic><topic>Candidiasis - drug therapy</topic><topic>Candidiasis - epidemiology</topic><topic>Candidiasis - mortality</topic><topic>Case-Control Studies</topic><topic>Catheters</topic><topic>Clinical Articles</topic><topic>Demography</topic><topic>Dosage</topic><topic>Human mycoses</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Infant, Premature, Diseases - drug therapy</topic><topic>Infant, Premature, Diseases - epidemiology</topic><topic>Infant, Premature, Diseases - mortality</topic><topic>Infant, Very Low Birth Weight</topic><topic>Infants</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Meningitis, Fungal - complications</topic><topic>Meningitis, Fungal - drug therapy</topic><topic>Meningitis, Fungal - epidemiology</topic><topic>Meningitis, Fungal - mortality</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Mycoses</topic><topic>Mycoses of the nervous system</topic><topic>Newborns</topic><topic>Pediatrics</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Bonita E.</creatorcontrib><creatorcontrib>Cheung, Po-Yin</creatorcontrib><creatorcontrib>Robinson, Joan L.</creatorcontrib><creatorcontrib>Evanochko, Christene</creatorcontrib><creatorcontrib>Robertson, Charlene M. T.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Bonita E.</au><au>Cheung, Po-Yin</au><au>Robinson, Joan L.</au><au>Evanochko, Christene</au><au>Robertson, Charlene M. T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative Study of Mortality and Morbidity in Premature Infants (Birth Weight, <1,250 g) with Candidemia or Candidal Meningitis</atitle><jtitle>Clinical infectious diseases</jtitle><addtitle>Clinical Infectious Diseases</addtitle><date>1998-09-01</date><risdate>1998</risdate><volume>27</volume><issue>3</issue><spage>559</spage><epage>565</epage><pages>559-565</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><coden>CIDIEL</coden><abstract>Little information is available on long-term neurodevelopment of premature neonates with invasive candidal infections. We retrospectively studied the outcomes for 25 premature neonates (birth weight, <1,250 g) with candidemia or candidal meningitis (cases) and compared them with 25 neonates matched for birth weight (±100 g) and gestational age (±1 week) (controls). Durations of antibiotic therapy, artificial ventilation, invasive catheterizations, and hyperalimentation were longer for cases than for controls. Cases had a higher final grade of intraventricular hemorrhage than did controls (median: 3.0 vs. 2.5, respectively; P < .05). Forty-four percent (11 of 25) of cases and 16% (4 of 25) of controls died (P > .05), and 29% (4 of 14) of surviving cases and 14% (3 of 21) of controls were disabled (P > .05). More cases had combined mortality and neurodevelopmental disabilities than did controls (60% vs. 28%, respectively; P < .05). Use of invasive therapies should be minimized for premature neonates at risk for invasive candidal infection that is associated with adverse outcomes.</abstract><cop>Chicago, IL</cop><pub>The University Chicago Press</pub><pmid>9770157</pmid><doi>10.1086/514712</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1058-4838 |
| ispartof | Clinical infectious diseases, 1998-09, Vol.27 (3), p.559-565 |
| issn | 1058-4838 1537-6591 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69959901 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | Biological and medical sciences Birth weight Blood Candida Candida - isolation & purification Candidemia Candidiasis - complications Candidiasis - drug therapy Candidiasis - epidemiology Candidiasis - mortality Case-Control Studies Catheters Clinical Articles Demography Dosage Human mycoses Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases - drug therapy Infant, Premature, Diseases - epidemiology Infant, Premature, Diseases - mortality Infant, Very Low Birth Weight Infants Infections Infectious diseases Medical sciences Meningitis, Fungal - complications Meningitis, Fungal - drug therapy Meningitis, Fungal - epidemiology Meningitis, Fungal - mortality Morbidity Mortality Mycoses Mycoses of the nervous system Newborns Pediatrics Retrospective Studies Risk Factors Treatment Outcome |
| title | Comparative Study of Mortality and Morbidity in Premature Infants (Birth Weight, <1,250 g) with Candidemia or Candidal Meningitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T11%3A34%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparative%20Study%20of%20Mortality%20and%20Morbidity%20in%20Premature%20Infants%20(Birth%20Weight,%20%3C1,250%20g)%20with%20Candidemia%20or%20Candidal%20Meningitis&rft.jtitle=Clinical%20infectious%20diseases&rft.au=Lee,%20Bonita%20E.&rft.date=1998-09-01&rft.volume=27&rft.issue=3&rft.spage=559&rft.epage=565&rft.pages=559-565&rft.issn=1058-4838&rft.eissn=1537-6591&rft.coden=CIDIEL&rft_id=info:doi/10.1086/514712&rft_dat=%3Cjstor_proqu%3E4460587%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17575497&rft_id=info:pmid/9770157&rft_jstor_id=4460587&rfr_iscdi=true |