Levosimendan Enhances Cardiac Performance After Cardiopulmonary Bypass: A Prospective, Randomized Placebo-Controlled Trial

Levosimendan is a new myofilament calcium (Ca) sensitizer that increases myocardial contractility by stabilizing the Ca-bound conformation of troponin C. We tested the hypothesis that levosimendan enhances cardiac performance after cardiopulmonary bypass (CPB). Anesthesia was induced and maintained...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1999-08, Vol.34 (2), p.219-228
Hauptverfasser:	Nijhawan, Niraj, Nicolosi, Alfred C, Montgomery, Matthew W, Aggarwal, Anil, Pagel, Paul S, Warltier, David C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Cardiopulmonary Bypass Cardiotonic agents Cardiotonic Agents - pharmacology Cardiovascular system Double-Blind Method Heart - drug effects Heart - physiology Hemodynamics - drug effects Humans Hydrazones - pharmacology Medical sciences Middle Aged Pharmacology. Drug treatments Prospective Studies Pyridazines - pharmacology Simendan Ventricular Function, Left
Online-Zugang:	Volltext
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