An Immunoluminometric Assay for Cardiotrophin-1: A Newly Identified Cytokine Is Present in Normal Human Plasma and Is Increased in Heart Failure

Cardiotrophin-1, a member of the interleukin-6 related cytokine family which acts via the glycoprotein 130 signalling pathway, may be involved in the process of ventricular remodelling. Its presence in human plasma has never been reported. We have devised a non-radioactive immunoluminometric sensiti...

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Veröffentlicht in:	Biochemical and biophysical research communications 1999-08, Vol.261 (3), p.567-571
Hauptverfasser:	Talwar, S., Downie, P.F., Squire, I.B., Barnett, D.B., Davies, J.D., Ng, L.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Amino Acid Sequence Animals Cardiac Output, Low - blood cardiotrophin-1 Cytokines - analysis Cytokines - blood Cytokines - chemistry Electrophoresis, Polyacrylamide Gel Female heart failure Humans Immunoassay - methods Immunosorbent Techniques Luminescent Measurements Male Middle Aged Molecular Sequence Data Molecular Weight Myocardium - chemistry plasma Rats Reference Values
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