In vitro evaluation of the haemopoietic defect of CD34+ cells from patients with acute myeloid leukaemia in first remission

Haemopoietic cells from patients with acute myeloid leukaemia (AML) in first complete remission (CR1) show in vitro a haemopoietic defect and a decreased expansion potential. To better characterize this haemopoietic defect, CR1 AML and normal CD34+ cells were analysed for immunophenotype, viability,...

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Veröffentlicht in:	British journal of haematology 1999-07, Vol.106 (1), p.142-151
Hauptverfasser:	HERMAN, P, VAN BOCKSTAELE, D. R, FERRANT, A, STRAETMANS, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute myeloid leukaemia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigens, CD34 Biological and medical sciences Bone marrow, stem cells transplantation. Graft versus host reaction cytokines ex vivo expansion haemopoiesis Hematology Hematopoiesis - physiology Hematopoietic Stem Cells - pathology Humans Interleukin-11 - pharmacology Leukemia, Myeloid - pathology Medical sciences Membrane Proteins - pharmacology Stem Cell Factor - pharmacology Transfusions. Complications. Transfusion reactions. Cell and gene therapy Tumor Cells, Cultured
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