An increase in [ [formula omitted]] CGS21680 binding in the striatum of postmortem brains of chronic schizophrenics

We measured adenosine 2a receptors in basal ganglia of 13 schizophrenics and 10 controls, using [ 3 H ] CGS21680 as a ligand for the receptor binding assay. There was a significant increase in the specific [ 3 H ] CGS21680 binding in the putamen and caudate, but not in the globus pallidus of externa...

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