Neuropathological changes in the nucleus basalis correlate with clinical measures of dementia

The present study correlates the severity of dementia in Alzheimer's disease with the degree of neuropathology present in the nucleus basalis of Meynert. We assessed neurofibrillary tangles, neuronal loss and morphometric changes in 21 patients with Alzheimer's disease who underwent extens...

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Veröffentlicht in:	Acta neuropathologica 1999-08, Vol.98 (2), p.186-196
Hauptverfasser:	IRAIZOZ, I, GUIJARRO, J. L, GONZALO, L. M, DE LACALLE, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - pathology Alzheimer Disease - psychology Alzheimer's disease Biological and medical sciences Cell Count Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia Dementia disorders Female Humans Male Measuring techniques Medical sciences Middle Aged Neurodegenerative diseases Neurofibrillary tangles Neurofibrillary Tangles - pathology Neurology Neurons - pathology Neuropathology Neuropsychological Tests Nucleus basalis Parahippocampal gyrus Psychological assessment Psychology Substantia Innominata - pathology
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