Cytogenetic clonality analysis in monosomy 7 associated with juvenile myelomonocytic leukemia: clonality in B and NK cells, but not in T cells

It remains unclear which lymphoid lineages are involved in juvenile myelomonocytic leukemia (JMML). We report a JMML patient who acquired monosomy 7 after intensive chemotherapy. In this case, the expression of monosomy 7 was analyzed in T, B and natural killer (NK) cells highly purified from periph...

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Veröffentlicht in:	Leukemia research 1998-10, Vol.22 (10), p.887-892
Hauptverfasser:	Nakazawa, Takayuki, Koike, Kenichi, Agematsu, Kazunaga, Itoh, Susumu, Hagimoto, Rokuro, Kitazawa, Yumi, Higuchi, Tsukasa, Sawai, Nobukuni, Matsui, Hiroko, Komiyama, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes Biological and medical sciences CD2 Antigens - blood Cell Lineage Chromosomes, Human, Pair 7 Clonality Clone Cells Fluorescence in situ hybridization Hematologic and hematopoietic diseases Humans In Situ Hybridization, Fluorescence Infant, Newborn Juvenile myelomonocytic leukemia Karyotyping Killer Cells, Natural Leukemia, Myelomonocytic, Chronic - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Monosomy Monosomy 7 T-Lymphocytes
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