Responses of Cardiac Protein Kinase C Isoforms to Distinct Pathological Stimuli Are Differentially Regulated

Currently at least 11 protein kinase C (PKC) isoforms have been identified and may play different roles in cell signaling pathways leading to changes in cardiac contractility, the hypertrophic response, and tolerance to myocardial ischemia. The purpose of the present study was to test the hypothesis...

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Veröffentlicht in:	Circulation research 1999-08, Vol.85 (3), p.264-271
Hauptverfasser:	Takeishi, Yasuchika, Jalili, Thunder, Ball, Nancy A, Walsh, Richard A
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - pharmacology Animals Biological and medical sciences Biological Transport - physiology Cardiology. Vascular system Coronary heart disease Enzyme Activation - physiology Guinea Pigs Heart Hemodynamics - drug effects Hemodynamics - physiology Hypoxia - enzymology Hypoxia - physiopathology In Vitro Techniques Isoenzymes - physiology Male Medical sciences Myocardial Ischemia - enzymology Myocardial Ischemia - physiopathology Myocardium - enzymology Oxidative Stress - physiology Protein Kinase C - metabolism Protein-Tyrosine Kinases - physiology Subcellular Fractions - enzymology Tissue Distribution - physiology Type C Phospholipases - physiology
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