Repeated-dose pharmacodynamics of clopidogrel in healthy subjects

The effect of repeated doses of clopidogrel, a novel platelet ADP-receptor antagonist, on platelet aggregation and its tolerance were assessed in two randomized, double-blind studies in healthy male adults. In each of the four successive dose groups in Study I, 6 subjects received either clopidogrel...

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Veröffentlicht in:	Seminars in thrombosis and hemostasis 1999, Vol.25 Suppl 2, p.9-14
Hauptverfasser:	Thebault, J J, Kieffer, G, Lowe, G D, Nimmo, W S, Cariou, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Cross-Over Studies Double-Blind Method Drug Administration Schedule Humans Male Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - pharmacology Ticlopidine - administration & dosage Ticlopidine - analogs & derivatives Ticlopidine - pharmacology
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