Messenger RNA Editing of the Human Serotonin 5-HT2C Receptor

RNA encoding the rat serotonin 5-HT2C receptor undergoes editing whereby one to four adenosines are converted to inosines. This conversion can change up to three codons out of a stretch of five in the second intracellular loop of the receptor. RNA editing of the rat 5-HT2C receptor that changes all...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 1999-08, Vol.21 (2), p.82S-90S
Hauptverfasser:	Fitzgerald, Lawrence W, Iyer, Geeta, Conklin, Deborah S, Krause, Carol M, Marshall, Anne, Patterson, John P, Tran, David P, Jonak, Gerald J, Hartig, Paul R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line Cell receptors Cell structures and functions Cloning, Molecular Efficacy Fundamental and applied biological sciences. Psychology Humans Intrinsic activity LSD mCPP Molecular and cellular biology Monoamines receptors (catecholamine, serotonine, histamine, acetylcholine) Polymerase Chain Reaction Protein Isoforms - genetics Protein Isoforms - metabolism Rats Receptor, Serotonin, 5-HT2C Receptors, Serotonin - genetics Receptors, Serotonin - metabolism Recombinant Proteins - metabolism RNA Editing RNA, Messenger - genetics RNA, Messenger - metabolism Serotonin - metabolism Serotonin Antagonists - metabolism Serotonin Antagonists - pharmacology Serotonin receptor Serotonin Receptor Agonists - metabolism Serotonin Receptor Agonists - pharmacology Transcriptional modification Transfection
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