Choice of endothelial marker is crucial for assessment of bone marrow microvessel density in chronic lymphocytic leukemia

Angiogenesis is a potential prognostic factor in chronic lymphocytic leukemia (CLL). Elevated circulating levels of angiogenic factors in CLL have been repeatedly reported. Nevertheless, the issue of bone marrow neovascularization in CLL remains controversial, partly due to limited number of publish...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2008-12, Vol.116 (12), p.1058-1062
Hauptverfasser:	SMOLEJ, L, KAŠPAROVÁ, P
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Antibodies, Monoclonal - immunology Antigens, CD34 - analysis Biological and medical sciences Biomarkers, Tumor - analysis blood coagulation factors Bone Marrow - blood supply Bone Marrow - pathology bone marrow biopsy CD34 Chronic lymphocytic leukemia Endothelium, Vascular - immunology Endothelium, Vascular - pathology Fundamental and applied biological sciences. Psychology Humans Immunohistochemistry In Situ Hybridization, Fluorescence Infectious diseases Leukemia, Lymphocytic, Chronic, B-Cell - pathology Medical sciences Microbiology microvessel density Microvessels - immunology Microvessels - pathology Neoplasm Staging neovascularization Neovascularization, Pathologic - diagnosis von Willebrand factor von Willebrand Factor - analysis
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