Gastric enterochromaffin-like-cell tumor with liver and splenic metastases

We report a patient with gastric enterochromaffin-like-cell tumor with liver and splenic metastases. He was 68 years old and presented with major complaints of epigastric pain and weight loss. Under the diagnosis of gastric carcinoma with liver metastasis, total gastrectomy with splenectomy and late...

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Veröffentlicht in:Journal of gastroenterology 1999-06, Vol.34 (3), p.383-386
Hauptverfasser: Eriguchi, N, Aoyagi, S, Hara, M, Sakai, T, Imayama, H, Tanaka, E, Hashimoto, M, Imamura, I, Kage, M
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container_end_page 386
container_issue 3
container_start_page 383
container_title Journal of gastroenterology
container_volume 34
creator Eriguchi, N
Aoyagi, S
Hara, M
Sakai, T
Imayama, H
Tanaka, E
Hashimoto, M
Imamura, I
Kage, M
description We report a patient with gastric enterochromaffin-like-cell tumor with liver and splenic metastases. He was 68 years old and presented with major complaints of epigastric pain and weight loss. Under the diagnosis of gastric carcinoma with liver metastasis, total gastrectomy with splenectomy and lateral segmentectomy of the liver was performed. Intraoperative findings resulted in a diagnosis of adenocarcinoma T3N2P0H1, in stage IVa. Histological examination of the resected specimens showed a well differentiated neuroendocrine carcinoma (enterochromaffin-like-cell tumor) with liver and splenic metastasis which demonstrated high-grade lymphatic and vascular invasion. There was no lymph node metastasis. The tumor cells in the stomach, liver and spleen were immunoreactive for chromogranin A and Grimelius--positive. We review the literature, as well as presenting this case report.
doi_str_mv 10.1007/s005350050279
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subjects Aged
Carcinoid Tumor - diagnosis
Carcinoid Tumor - pathology
Carcinoid Tumor - secondary
Carcinoid Tumor - surgery
Enterochromaffin Cells - pathology
Follow-Up Studies
Gastrectomy
Gastroscopy
Humans
Liver Neoplasms - diagnosis
Liver Neoplasms - secondary
Liver Neoplasms - surgery
Male
Splenic Neoplasms - diagnosis
Splenic Neoplasms - secondary
Splenic Neoplasms - surgery
Stomach Neoplasms - diagnosis
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Treatment Outcome
title Gastric enterochromaffin-like-cell tumor with liver and splenic metastases
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